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Pharmacology, Unit 2 > Inflammation - MOA > Flashcards

Inflammation - MOA Flashcards

1
Q

Ibuprofen

A

Reversibly inhibit COX1/COX2, especially COX1

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2
Q

Flurbiprofen

A

Reversibly inhibit COX1/COX2, especially COX1

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3
Q

Piroxican

A

Reversibly inhibit COX1/COX2, especially COX1

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4
Q

Acetylsalicylic acid

A

1) irreversibly acetylates COX1/COX2

2) salicylic acid (metabolite) reversibly inhibits COX1/COX2

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5
Q

Celecoxib

A

selectively inhibits COX2

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6
Q

Acetaminophen

A

Reversibly inhibit COX1/COX2, especially COX1

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7
Q

Naproxen

A

Reversibly inhibit COX1/COX2, especially COX1

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8
Q

Oxaprozin

A

Reversibly inhibit COX1/COX2, especially COX1

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9
Q

Etoricoxib

A

selectively inhibits COX2

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10
Q

Diflunisal

A

salicylic acid derivative that reversibly inhibits COX1/COX2

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11
Q

Sulindac

A

Reversibly inhibit COX1/COX2, especially COX1

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12
Q

Ketorolac

A

Reversibly inhibit COX1/COX2, especially COX1

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13
Q

Indomethacin

A

Reversibly inhibit COX1/COX2, especially COX1

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14
Q

Which proprionic acid derivative has the longest half-life? The second longest?

A

Longest half-life: Oxaprozin

2nd longest: Naproxen

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Pharmacology, Unit 2 (22 decks)

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