Lymphatic and Immune System Quiz Flashcards

1
Q

Functions of Lymphatic System

A

Immunity
Lipid absorption
Fluid recovery

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2
Q

Organs Involved in Lymphatic System

A
Red bone marrow
Thymus
Tonsils
Spleen
Lymph nodes
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3
Q

Lymph

A

Clear, colorless fluid, similar to plasma but much less protein

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4
Q

Lymphatic Capillaries

A

Closed at one end
Tethered to surrounding tissue by protein filaments
Endothelial cells loosely overlapped

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5
Q

Lymphatic Vessels

A

Larger ones composed on tunica interna, tunica media, and tunica externa

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6
Q

Route of Lymph Flow

A

Lymphatic Capillaries
Collecting Vessels
Lymphatic Trunks
Collecting Ducts (Right Lymphatic and Thoracic)

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7
Q

Mechanisms of Lymph Flow

A

Low pressure and low speed
Aided by pumps
Moved along by rhythmic contractions of lymphatic vessels

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8
Q

Lymphatic Cells (Lymphocytes)

A

Natural Killer Cells
T Lymphocytes
B Lymphocytes
Antigen Presenting Cells

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9
Q

Lymphatic Tissue

A

Aggregations of lymphocytes in mucus membranes and CT of many organs

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10
Q

Lymph Nodes

A

Bean-shaped organs located around lymphatic vessels
Cortex and medulla
Flow is in one direction
Filter lymph

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11
Q

Palatine Tonsils

A

Pair at the posterior margin of the oral cavity

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12
Q

Lingual Tonsils

A

Pair at the root of the tongue

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13
Q

Pharyngeal Tonsil

A

Single tonsil on the wall of the pharynx (adenoid)

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14
Q

Thymus Gland

A

Two lobed organ in the mediastinum

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15
Q

Spleen

A

Red pulp filled with erythrocytes
While pulp filled with lymphocytes and macrophages
Blood reservoir and filters blood

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16
Q

2nd Line of Defense

A

Neutrophils, Eosinophils, Basophils, Macrophages

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17
Q

Neutrophils

A

Phagocytize bacteria
Create a killing zone
Kills itself

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18
Q

Eosinophils

A

Found in mucus membranes

Phagocytizes antigen-antibody complexes, allergens, and chemicals

19
Q

Basophils

A

Secrete chemicals to attract leukocytes

Secrete histamine, leukotrienes, heparine

20
Q

Macrophages

A

Displays foreign antigens
Secretes cytokines
Induces fever
Form outside of the circulatory system

21
Q

Interferons

A

Produced by virally infected cells

Diffuse to neighboring cells to induce synthesis of antiviral proteins

22
Q

Complement Proteins

A

Inactive proteins in blood plasma

When activated enhance immune, allergic, and inflammatory reactions

23
Q

Antiviral Effect

A

Generalized protection
Activate natural killer cells and macrophages
Destroy infected host cells

24
Q

Anticancer

A

Stimulate destruction of cancer cells

25
Pathways of Complement Activation
Classical pathway Alternate pathway Leptin pathway
26
Mechanisms of Action
Enhanced inflammation Opsonization Cytolysis Phagocytosis
27
Classical Pathway
Begins with activation of C1 | Specific response
28
Alternate Pathway
Begins with activation of C3
29
Leptin Pathway
Binds carbohydrates on the pathogen surface
30
C3A
Leads to inflammation
31
C3B
Leads to immune clearance Phagocytosis Cytolysis
32
Membrane Attack Complex
Complement proteins C5B to C9 form ring in plasma membrane of enemy cell causing cytolysis
33
Natural Killer Cells and Phagocytes
NK cells kill a variety of microbes and tumor cells | Phagocytes are neutrophils and macrophages
34
Phagocytosis
Chemotaxis Adherence Ingestion Digestion and Killing
35
Chemotaxis
Attraction to chemicals from damaged tissues, complement proteins, or microbial products
36
Adherence
Attachment to plasma membrane of phagocyte
37
Ingestion
Engulf by pseudopods to form phagosome
38
Digestion and Killing
Merge with lysosome containing digestive enzymes and form lethal oxidants Exocytosis residual body
39
Inflammation
Defensive response to tissue injury Limits speed of pathogens, then destroys them Removes debris and initiates tissue repair
40
Cardinal Signs of Inflammation
Redness (caused by increased blood flow) Swelling (caused by increased capillary permeability and filtration) Heat (caused by increased blood flow) Pain (caused by inflammatory chemicals: bradykinin and prostaglandins)
41
Fever
Promotes interferon activity Accelerates metabolic rate and tissue repair Inhibits pathogen reproduction
42
Course of a Fever
1. Infection and pyrogen secretion 2. Hypothalamic thermostat is reset to higher set point 3. Onset (body temperature rises) 4. Stadium (body temperature oscillates around new set point) 5. Infection ends, set point returns to normal 6. Defervescence (body temperature returns to normal)
43
Mobilization of Defenses
Bradykinin, histamine, and leukotrienes are secreted by damaged cells, basophils, and mast cells