liver function

Question 1

the only organ that can regenerate

Answer 1

liver

Question 2

weight of liver

Answer 2

1.2 to 1/5 kg

Question 3

size of right lobe of the liver to left lobe

Answer 3

6x times bigger than the left

Question 4

Contributes approx. of 25% of the blood
supply and provides most of the O2
requirement

Answer 4

hepatic artery

Question 5

Transports the most recently absorbed
material 75% from the intestines to the
liver

Answer 5

Portal vein

Question 6

major functioning cells;
performs most of the metabolic and
synthetic functions of the liver

Answer 6

Hepatocytes

Question 7

Contains lysosomes with hydrolytic
enzymes, immunoglobulin and
complement receptors

Answer 7

Kupffer Cells

Question 8

site of fat soluble vitamins

Answer 8

Stellate cells (Ito cells)

Question 9

Synthesize collagen > fibrosis > cirrhosis

Answer 9

Stellate cells (Ito cells

Question 10

Synthesize nitric oxide > regulate
intrahepatic blood flow

Answer 10

Stellate cells (Ito cells)-

Question 11

liver progenitor cells involved
in the regeneration of hepatocytes and bile
ducts after liver injury

Answer 11

Oval cells

Question 12

a system of liver that is about the metabolic activities

Answer 12

.Biochemical Hepatocytic System

Question 13

a system of liver that is about the metabolism of bilirubin

Answer 13

Hepatobiliary System

Question 14

a system of liver that is about the immune system

Answer 14

Reticuloendothelial System

Question 15

METABOLIC FUNCTIONs of the liverr

Answer 15

Carbohydrate Metabolism
Protein synthesis
Lipid metabolism

Question 16

in the liver, there will be a pool of amino acids through __

Answer 16

protein degradation

Question 17

liver Catabolize fatty acids to acetyl CoA and cholesterol to form ____

Answer 17

primary bile acids

Question 18

Phagocytosis by ___

Answer 18

Kupffer cells

Question 19

the first organ to metabolized foods is

Answer 19

liver - first pass metabolism

Question 20

Helps to regulate blood volume by serving as a ___

Answer 20

blood storage area

Question 21

Bile is made up of ______, and other
substances extracted from the blood.

Answer 21

bile acids or salts, bile
pigments, cholesterol

Question 22

The body produces approximately ____ of bile
per day and excretes ____ of what is
produced

Answer 22

3 L; 1 L

Question 23

The liver serves as a ___ between substances absorbed by the gastrointestinal tract and those released into systemic circulation

Answer 23

gatekeeper

Question 24

Every substance that is absorbed in the gastrointestinal tract must
first pass through the liver; this is referred to as ___.

Answer 24

first pass

Question 25

This is an important function of the liver because it can allow
important substances to reach the systemic circulation and can
serve as a barrier to prevent toxic or harmful substances from
reaching systemic circulation

Answer 25

first pass of the liver

Question 26

Bile components ___

Answer 26

bile acids, lecithin, cholesterol, bilirubin, and
electrolytes

Question 27

Bile is important in __ digestion

Answer 27

lipid

Question 28

Bile pigment that
results from the
catabolism of the
heme moiety of the
hemoglobin
molecule due to old
age or trauma

Answer 28

Bilirubin

Question 29

characterized by a mild unconjugated hyperbilirubinemia

Answer 29

Gilbert’s Syndrome

Question 30

Characterized by decreased conjugation and decreased
uptake of bilirubin

Answer 30

Gilbert’s Syndrome

Question 31

Pre-conjugation failure

Answer 31

Gilbert’s Syndrome

Question 32

o Characterized by a decreased hepatic excretion of bilirubin

Answer 32

Dubin-Johnson Syndrome

Question 33

Increased B2 with hepatic pigmentation (melanin

Answer 33

Dubin-Johnson Syndrome

Question 34

Cause is still unknown

oSimilar to Dubin-Johnson but without hepatic pigmentation

Answer 34

Rotor Syndrome

Question 35

A familial form of unconjugated hyperbilirubinemia caused by a
circulating inhibitor of bilirubin conjugation

Answer 35

Lucey-Driscoll Syndrome

Question 36

GGT is number 1 marker of

Answer 36

alcoholic hepatitis

Question 37

most sensitive marker of hepatocytic injury

Answer 37

ALT alanine transaminase - SGPT

Question 38

function of accelerator

Answer 38

to measure the total bilirubin fraction