Liver 2 Flashcards
Feathery degeneration in the peri portal hepatocytes is seen in?
Cholestasis
Cytoplasmic swelling + Mallory bodies + bile infarcts
Severe Cholestasis
Stromal edema and neutrophils + ductular proliferation
Cholestasis
Most common causes of L. Bile duct obstruction in adults
Gallstones - Malignancies - strictures
Most common causes of L. Bile duct obstruction in children
Biliary atresia - Cystic fibrosis - Choledocal cyst
Common organisms causing ascending cholangitis
Coliforms + Enterococci
The histologic hallmark of ascending cholangitis
Influx of peri ductular neutrophils into the bile duct epithelium
Fibrosis of the bile duct obstruction is?
Peri portal
Jigsaw puzzle appearance
Biliary cirrhosis
IBD is more common in?
- PBC.
- PSC.
PSC
More common in females?
- PSC.
- PBC.
PBC
AMA is positive in 95% in?
- PSC.
- PBC.
PBC
PBC s and s
Pruritus - skin hyperpigmentations - xanthelasma
Lymphocytic inflammation + granulomas + florid duct lesion
PBC
Beading in radiographs is seen in?
- PBC.
- PSC.
PSC