Liver 2 Flashcards

1
Q

Feathery degeneration in the peri portal hepatocytes is seen in?

A

Cholestasis

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2
Q

Cytoplasmic swelling + Mallory bodies + bile infarcts

A

Severe Cholestasis

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3
Q

Stromal edema and neutrophils + ductular proliferation

A

Cholestasis

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4
Q

Most common causes of L. Bile duct obstruction in adults

A

Gallstones - Malignancies - strictures

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5
Q

Most common causes of L. Bile duct obstruction in children

A

Biliary atresia - Cystic fibrosis - Choledocal cyst

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6
Q

Common organisms causing ascending cholangitis

A

Coliforms + Enterococci

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7
Q

The histologic hallmark of ascending cholangitis

A

Influx of peri ductular neutrophils into the bile duct epithelium

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8
Q

Fibrosis of the bile duct obstruction is?

A

Peri portal

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9
Q

Jigsaw puzzle appearance

A

Biliary cirrhosis

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10
Q

IBD is more common in?

  • PBC.
  • PSC.
A

PSC

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11
Q

More common in females?

  • PSC.
  • PBC.
A

PBC

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12
Q

AMA is positive in 95% in?

  • PSC.
  • PBC.
A

PBC

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13
Q

PBC s and s

A

Pruritus - skin hyperpigmentations - xanthelasma

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14
Q

Lymphocytic inflammation + granulomas + florid duct lesion

A

PBC

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15
Q

Beading in radiographs is seen in?

  • PBC.
  • PSC.
A

PSC

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16
Q

Onion skin fibrosis

A

Small duct (PSC)

17
Q

Outpouchings of the mucosal epithelium through the wall ( Rokitansky-Aschoff sinuses )

A

Chronic cholecystitis

18
Q

Adenoma pf the gallbladder has increased prevalence in?

A

FAP + PJS

19
Q

Numerous Rokitansky-Aschoff sinuses accompanied by smooth muscle hyperplasia is seen in?

A

Adenomyomatosis

20
Q

Most carcinomas of the gallbladder are?

A

Adenocarcinomas

21
Q

Most common cause of chronic pancreatitis

A

Chronic alcohol abuse

22
Q

Benign - Tail - women - painful - cuboidal cells

A

Serous

23
Q

Women - painless - tail - thick mucin - columnar cells

A

Mucinous

24
Q

Mucin producing - men - head - similar to ovarian stroma

A

Intraductal

25
Q

Non invasive + small ducts

A

Intra epithelial

26
Q

Most carcinomas of the head of the pancreas obstruct?

A

The distal CBD