Hematology 1

Question 1

Q: in the lymph nodes, the B lymphocytes are concentrated into?

• The cortical follicles.
• The para cortex area.
• Both of the above.
• Non of the above.

Answer 1

The cortical follicles

Question 2

Q: in the lymph nodes, the T lymphocytes concentrated into?

• Para cortex or interfollicular areas.
• Cortical follicles.
• Both of the above.
• Non of the above.

Answer 2

Para cortex or interfollicular areas.

Question 3

Q: Which type of reactive growth patterns of the following is present in rheumatoid disease and AIDS?

• Follicular hyperplasia.
• Inter follicular hyperplasia.
• Sinusoidal hyperplasia.
• Mixed hyperplasia.

Answer 3

Follicular hyperplasia

Question 4

Q: Which of the following will NOT show lymph nodes growth pattern of interfollicular hyperplasia?

• EBV infection.
• CMV infection.
• HIV infection.
• SLE.

Answer 4

HIV infection

Question 5

Q: Which of the following causes Mixed hyperplasia of the lymph nodes?

• RA.
• Toxoplasmosis.
• Cat scratch disease.
• B and C.

Answer 5

B and C

Question 6

Q: Which of the following cells has a predominant role in “Humoral adaptive immunity”?

• B cells.
• T cells.
• NK cells.
• All of the above.

Answer 6

B cells

Question 7

Q: Which of the following has a predominant role in “cell mediated adaptive immunity” ?

• B cells.
• T cells.
• NK cells.
• Non of the above.

Answer 7

T cells

Question 8

Q: which of the following T cells is responsible for releasing cytokines ?

• T helper.
• T cytotoxic.
• T regulatory.
• All of the above.

Answer 8

T helper CD4

Question 9

Q: which of the following is considered the first line defense that lacks specificity and memory?

• B cells.
• T cells.
• NK cells.
• Non of the above.

Answer 9

NK cells

Question 10

Mantle cell Lymphoma

Answer 10

Pre GC neoplasms

Question 11

Follicular lymphoma.
Hodgkin’s lymphoma.
Burrkett Lymphoma.
DLBCL.

Answer 11

GC neoplasms

Question 12

Marginal zone and MALT Lymphomas.
CLL.
Plasma cell myeloma.

Answer 12

Post GC neoplasms

Question 13

CD10
CD20
CD45
CD79a
BCL6

Answer 13

B cells markers in GC

Question 14

CD3
CD4
CD5
CD8
CD45

Answer 14

T cell markers in interfollicular region

Question 15

Discrete + painless + rubbery cervical lymph nodes.

Answer 15

Classical HL

Question 16

CD30 McAb staining

Answer 16

To stain RS cells and HC.

Question 17

Owl eye appearance is a characteristic of

Answer 17

RS cells

Question 18

NF kapa B activation leads to

Answer 18

Prevention of apoptosis in CHL

Question 19

HC and RS cells are derived from

Answer 19

The GC B cells

Question 20

Crippled B cells is a characteristic of

Answer 20

CHL

Question 21

Lymphocyte predominant cells is a characteristic of

Answer 21

NLPHL

Question 22

5% transformed into DLBCL

Answer 22

NLPHL

Question 23

Lymphoma cells with clefts & folded nuclei are from

Answer 23

T cell Lymphoma

Question 24

Loosely woven chromatin and multiple prominent nucleoli are from

Answer 24

DLBCL

Question 25

t (14:18), t (8:14), c-myc, t (3:14), BCL2, BCL6

Answer 25

DLBCL (aggressive)

Question 26

t (14:18) + BCL2 over expression

Answer 26

Follicular lymphoma (indolent)

Question 27

Trisomy 12, del 13q

Answer 27

SLL (indolent)

Question 28

t (1:14) + BCL10 mutation

Answer 28

MALT lymphoma (indolent)

Question 29

t (8:14) + c-myc

Answer 29

Burrkett Lymphoma (aggressive)

Question 30

t (11:14), BCL1 oncogene deregulation, cyclin-D1 overexpression.

Answer 30

Mantle cell Lymphoma (aggressive)

Question 31

Paratrabecular infiltration of small lymphocyte in the BM is a clinical feature of?

Answer 31

NHL