GIT 2 Flashcards
Crohn’s disease has ……. of a genetic basis than UC.
More
A gene associated with Crohn’s disease
NOD2
A 22 y old patient, presented to the ER CO/ intermittent diarrhea, fever and abdominal pain. On macroscopic examination, there was cobblestone appearance of the mucosa, deep fissures and fistulas. There was also adhesions of the covering serosa. What is the most likely diagnosis?
Crohn’s disease
Extra intestinal manifestations of IBD
Uveitis. Migratory polyarthritis. Sacroiliitis. Erythema nodosum. Ankylosing spondylitis. Primary sclerosing cholangitis.
Painful, tender, bright red and bilateral symmetrical nodules
Erythema nodosum
The most common areas affected in Crohn’s disease
Terminal ileum + cecum
Creeping fat is a characteristic of?
Crohn’s disease
Non caseating granulomas are a characteristic of?
Crohn’s disease
A 22 y old patient, presented to the ER CO/ bloody diarrhea with abdominal cramping and pain. Macroscopic examination of the colon biopsy reveals congested mucosa with broad based ulcers and pseudopolyps. There was NO fissures or fistulas. The most likely diagnosis is?
Ulcerative colitis
Toxic megacolon is more common in?
UC
Crypt abscess is more common in?
UC
Malignant risk is more in?
UC
Primary symptom of IBD
Bloody diarrhea of > 6 months
Paneth cell metaplasia is seen in
CD + UC
Architectural distortion is more in?
UC