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Pathology > GIT 3 > Flashcards

GIT 3 Flashcards

1
Q

Types of polyps

A

Hyperplastic.
Inflammatory.
Hamartomatous.
Lymphoid.

Adenomatous or adenomas.
“Neoplastic”

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2
Q

Most common type of polyps

A

Hyperplastic polyps

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3
Q

Small, nipple-like hemispheric polyps, common in rectosegmoid colon

A

Hyperplastic polyps

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4
Q

Has a serrated epithelial profile and an irregular crypt architecture

A

Hyperplastic polyps

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5
Q

Sporadic, large rounded polyps with stalks, common in children

A

Hamartomatous polyps

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6
Q

melanotic mucosal and cutaneous pigmentation around the lips, oral mucosa, face, genitalia, and palmar surfaces of the hands.

A

Peutz Jeghers polyps

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7
Q

Types of adenomas

A

Tubular.
Villous.
Tubulovillous.
Sessile Serrated.

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8
Q

The more common and dangerous type of adenomas

A

Tubular adenoma

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9
Q

Most tubular adenomas are

A

Small and pedunculated

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10
Q

Most villous adenomas are

A

Large and sessile

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11
Q

The malignant risk of the adenomatous polyps depend on

A

Size.
Histologic architecture.
Dysplasia.

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12
Q

FAP classified into

A

Classic.
Attenuated.
Gardner syndrome.
Turcot syndrome.

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13
Q

FAP + multiple osteomas + epidermal cysts

A

Gardner syndrome

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14
Q

FAP + tumors in the CNS (medulloblastomas)

A

Turcot syndrome

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15
Q

APC mutation

A

FAP

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16
Q

Mismatch repair gene defect (MMRd)

A

HNPCC (Lynch syndrome)

17
Q

Mucus in the cytoplasm, pushing the nucleus aside is seen in

A

Signet ring carcinoma

18
Q

Intestinal polyps are more common in

A

Older adult + rectosegmoid

19
Q

Isolated hamartomatous polyps found in colon of adults

A

Retention polyps

20
Q

Hamartomatous polyps common in

A

Rectum

21
Q

Which type of polyps is seen in PJ syndrome

A

Hamartomatous

22
Q

PJ syndrome patients are at risk of?

A

Intussusception

23
Q

The stalk of tubular adenomas is composed of

A

Vascular fibromuscular tissue

24
Q

The most worrisome lesion regarding adenomatous polyps

A

Sessile polyp > 4cm

25
Q

Mismatch repair defect gene mutation is associated with?

A

CRC (sporadic) especially HNPCC

26
Q

Which type of large bowl tumor will turn 100% to malignant

A

FAP

27
Q

500 - 2500 colonic polyps most of them are tubular adenomas are seen in

A

Classic FAP

28
Q

Attenuated FAP is more common in

A

Proximal colon

29
Q

Mucinous tumur of the colon

A

HNPCC

30
Q

The commonest familial CRC

A

HNPCC (lynch syndrome)

31
Q

Total colectemy is used to treat

A

HNPCC

32
Q

Napkin ring constrictions are seen in

A

Distal colon (annular + encircling)

33
Q

Tumor in the proximal colon tend to be

A

Polypoid + exophytic

34
Q

Adenosquamous carcinomas is more in …… colon

A

Distal

35
Q

Anorectal canal tumors are

A

SCC

Pathology (24 decks)

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