limbic system Flashcards

1
Q

limbic lobe composed of

A

a more primitive portion of the cortex, and it includes the:
- cingulate gyrus,
- retrosplenial gyrus,
- subcallosal gyrus, and
- parahippocampal gyrus

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2
Q

limbic lobe definition

A
  • introduced by Broca
  • telencephalic structures that circle the foramen of Monro and border diencephalon
  • comprised of gray matter
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3
Q

limbic system definition

A
  • structures that interface between the cortex and the hypothalamus and modulate the motivational and emotional functions initiated by the hypothalamus
  • includes all structures that are linked to limbic lobe that project to hypothalamus or its targets
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4
Q

limbic system function

A
  • receive cortical input and modulate hypothalamic functions
  • control of emotion, motivated behavior, and memory
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5
Q

observations of limbic system clinically

A
  • lesion: results in no paralysis or sensory deficits
  • seizure/electrical: do no produce clonic movements or sensory perceptions
  • excitation: evokes emotional states or memory fragments
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6
Q

anatomy of hippocampus

A
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7
Q

papez circuit

A
  • controls motivation and emotion
  • Start: hippocampus (HPC) interlocking cell layers.
  • Output = fornix
  • Fornix > mammillary bodies > anterior nucleus of the thalamus via the mammillothalamic tract (MThT)
  • fibers > internal capsule to the cingulate
    gyrus
  • Cingulate gyrus > the entorhinal cortex >
    hippocampus.
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8
Q

See slides 12-20 for cross section images and labels

A
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9
Q

Henry Molaison

A
  • removal of hippocampus to prevent spreading of seizures
  • symptoms: Severe memory deficit, Loss of memory consolidation, No emotional issues
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10
Q

declarative memory

A
  • short term memory consolidated to long term memory
  • if you study it will be short term but repetitively it will be consolidated into long term memory
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11
Q

place cells of hippocampus

A
  • if you have an issue with short term memory (like HM after removal of hippocampus) you will still have long term memory
  • you can still navigate places from long term memory, but won’t be able to use short term memory
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12
Q

role of hippocampus

A
  • memory consolidation
  • spatial navigation
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13
Q

uncus

A
  • next to the parahippocampal gyrus
  • Inside the uncus is the amygdala
  • Uncus = hook
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14
Q

location of amygdala in cross section

A
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15
Q

amygdala pathways

A
  • stria terminalis
  • ventral amydalofugal pathway
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16
Q

major inputs and outputs of amygdala

A
  • hypothalamus
  • brainstem
  • hippocampus and entorhinal cortex
  • mediodorsal nucleus of thalamus
  • anterior cingulate cortex
  • prefrontal cortex
  • olfactory tract
17
Q

role of amygdala

A

the integrative center for emotions, emotional behavior, and motivation

18
Q

Kluver-Bucy syndrome

A
  • removal of amygdala
    symptoms:
  • Tameness
  • loss of fear and other emotional reactions
  • hypersexual
  • bulimia
  • Toral tendencies
  • hypermetamorphosis: short attention span
19
Q

amygdala can also cause/have:

A
  • temporal lobe epilepsy
  • lesions
20
Q

temporal lobe epilepsy symptoms

A
  • aggression
  • panic attacks
21
Q

lesions of amygdala symptoms

A
  • placidity
  • flatness of affect
  • failure to discriminate emotional expressions
  • loss of emotional memory processing