Lesson 15-16 Part I Flashcards
rostral
toward the forehead
caudal
toward the spinal cord
cerebrum
largest part of the brain, 83% of brain volume
name all the parts of the cerebrum (5)
- cerebral hemispheres
- gyri
- sulci
- longitudinal cerebral fissure
- corpus callosum
cerebral hemispheres
pairs of half globes of the cerebrum
gyri
thick folds on the cerebrum surface
sulci
shallow grooves between gyri
longitudinal cerebral fissure
the deep groove that separates cerebral hemispheres
corpus callosum
thick nerve bundle at the bottom of the longitudinal fissure that connects hemispheres
cerebellum
second largest part of the brain; separated from cerebrum by transverse cerebral fissure; also has fissures, sulci, gyri
the cerebellum is separated from the cerebrum buy the _____ _____ _____
transverse cerebral fissure
brainstem
smallest portion of the brain
what does the brainstem include?(3)
midbrain, pons, and medulla oblongata
gray matter
contains nerve cell bodies, dendrites, and unmyelinated axons, synapses
cortex
surface layer of gray matter in the cerebrum and cerebellum
nuclei
deeper masses of gray matter, surrounded by white matter
white matter
bundles of myelinated nerve fibers that connect one part of the brain to another and to the spinal cord
what is white matter composed of?
tracts, bundles of myelinated nerve fibers
the nervous system developed from the _____, the outermost tissue layer of the embryo
ectoderm
by the fourth week, the neural tube that was formed from the ectoderm exhibits three primary vesicles at its anterior end:
- forebrain (prosencephalon)
- midbrain (mesencephalon)
- hindbrain (rhombencephalon)
by the fifth week, the forebrain divides into two vesicles:
telencephalon and the diencephalon
by the fifth week, the midbrain…
remains undivided and retained the name mesencephalon
by the fifth week, the hindbrain divides into two vesicles:
metencephalon and myelencephalon
meninges
the three membranes surrounding the brain and spinal cord that lie between the nervous tissue and bone
from outermost to innermost, the meninges are called…
- dura mater
- arachnoid mater
- pia mater
what do meninges do?
protect the brain and provide a structural framework for its arteries and veins
the dura mater is composed of two layers:
periosteal layer and meningeal layer
dura mater: periosteal layer
equivalent to the periosteum of cranial bones
dura mater: meningeal layer
continues into vertebral canal and forms the dural sheath around the spinal cord
dural sinues
spaces located where periosteal and meningeal layers separate
_____ _____ _____ and _____ _____ collect blood circulating through the brain
superior sagittal sinus, transverse sinus
where is the dura mater attached to bone? (4)
- foramen magnum
- sella turcica
- crista galli
- sutures of the skull
falx cerebri
separates the two cerebral hemispheres
tentorium cerebelli
separates cerebrum from cerebellum
falx cerebelli
separates left and right halves of the cerebellum
arachnoid mater
transparent membrane over the brain surface
the _____ _____ separates the arachnoid mater from the pia mater below it
subarachnoid space
the subarachnoid space is filled with _____ _____ and blood vessels
cerebrospinal fluid
pia mater
very thin membrane, not usually visible without a microscope that is on the surface of the brain/spinal tissue
characteristics of the pia mater (2)
- follows the contours of the brain
- follows arteries as they penetrate into the cerebrum
meningitis
inflammation of the meninges; serious disease of infancy and childhood
what is meningitis caused by?
bacterial or viral invasion of the CNS through the nose and throat, mostly affecting the pia and arachnoid mater
what are signs and symptoms of meningitis? (7)
- swelling of the brain
- enlargement of the ventricles
- hemorrhage
- high fever
- stiff neck
- drowsiness
- intense headache
how do they diagnose meningitis?
examining the cerebral spinal fluid obtained by lumbar puncture (spinal tap)
ventricles
four internal, fluid-filled chambers of the brain
lateral ventricles
one in each cerebral hemisphere
third ventricle
narrow medial space beneath corpus callosum
fourth ventricle
small triangular chamber between pons and cerebellum
interventricular foramen
pore that connects lateral ventricles to the third ventricle
cerebral aqueduct
tube running through the midbrain that connects third ventricle to the fourth ventricle
central canal
tube that connects to the fourth ventricle and runs through the center of the spinal cord
cerebrospinal fluid (CSF)
clear, colorless liquid that fills the ventricles, canals of the CNS and bathes its external surface
ependymal cells
neuroglia that line ventricles and cover the choroid plexus; produce CSF
how does the production of CSF begin?
filtration of blood plasma through capillaries of the brain
what happens after blood plasma is filtered for CSF?
ependymal cells modify the filtrate; compared to plasma, CSF has more sodium and chloride, less potassium, calcium, glucose, and very little protein
choroid plexus
spongy mass of blood capillaries on the floor of each ventricle
how is CSF pushed through the CNS?
driven by its own pressure, beating of ependymal cilia, and pulsation of the brain produced by each heartbeat
CSF path through the ventricles (4)
- secreted in lateral ventricles
- through the intervertebral foramina into the third ventricle
- down the cerebral aqueduct into the fourth ventricle
- third and fourth ventricles add more CSF along the way
all CSF ultimately escapes through _____ pores that lead into the _____ _____ of the brain and spinal cord surface
three, subarachnoid space
what are the three pore CSF escapes through
- median aperture
- two lateral apertures
CSF is reabsorbed by _____ _____, extensions of the arachnoid meninx
arachnoid granulations
arachnoid granulations
extensions of the arachnoid meninx that protrude through the dura mater into the superior sagittal sinus
functions of the CSF: buoyancy
- allows brain to attain considerable size without being impaired by its own weight
- if brain rested on the cranium floor, pressure would kill the nervous tissue
functions of the CSF: protection
- protects brain from striking cranium when head is jolted
- shaken baby syndrome and concussion still occur from severe jolting
functions of the CSF: chemical stability
- flow of CNS rinses away metabolic wastes from nervous tissue and homeostatically regulates the chemical environment
the brain is supplied with blood by the _____ _____ _____ and _____ _____
internal carotid arteries, vertebral arteries
brain barrier system (BBS)
regulates what substances can get from the bloodstream into the tissue fluid of the brain
the brain barrier system is selectively permeable…
highly permeable to water, glucose, amd lipid-soluble substances like oxygen, CO2, alcohol, caffein, nicotine, and anesthetics
slightly permeable to sodium, potassium, chloride, wate products like urea, and creatinine
two points of entry to the brain must be guarded:
- blood capillaries throughout the brain tissue, guarded by the blood-brain barrier
- capillaries of the choroid plexus, guarded by the blood-CSF barrier
blood-brain barrier
protects the brain at the blood capillaries
consists of tight junctions between endothelial cells that form the capillary walls
blood-CSF barrier
protects the brain at the choroid plexus
formed by tight junctions between ependymal cells
stroke (cerebral vascular accident, CVA)
sudden death of brain tissue due to interruption of blood supply; second greatest cause of death
hemorrhagic stroke
rupture of a cerebral or subarachnoid blood vessel
ischemic stroke
obstruction of a blood vessel by a blood clot of lipid deposit
medulla oblongata
adult brain region that develops from embryonic myelencephalon
functions of the medulla oblongata (5)
- relays info to/from the brain and spinal cord
- coordinates complex autonomic reflexes
- controls visceral functions
- contains autonomic centers that control heart rate, blood pressure, respiration, and reflexes
- contains sensory and motor nuclei for cranial nerves
pons
adult brain region that develops from the embryonic metencephalon
characteristics of the pons (4)
- sensory and motor nuclei of cranial nerves V, VI, VII, and VIII
- nuclei involved with respiration
- nuclei that process and relay information to and from the cerebellum
- ascending, descending, and transverse tracts link nuclei of pons with the opposite cerebellar hemisphere
_____ _____ and _____ _____ function to modify respiratory rhythmicity
apneustic center, pneumotaxic center
the _____ _____ in the pons contains additional nuclei concerned with sleep, respiration, and posture
reticular formation
midbrain
brain region that develops from the embryonic mesencephalon; short segment of the brainstem that connects hindbrain to forebrain
midbrain: cerebral aqueduct
surrounded by central (periaqueductal) gray substance involved in pain awareness
tectum
roof-like part of the midbrain posterior to cerebral aqueduct
tectum: superior colliculi
two; visual attention, tracking moving objects, and visual reflexes
tectum: inferior colliculi
two; relays signals from inner ear to thalamus and other parts of the brain, auditory reflexes
tegmentum
connections go to and from the cerebellum for motor control
substantia nigra
dark nucleus pigmented with melanin; motor center that relays inhibitory signals to thalamus and basal nuclei, suppressing unwanted body movements
reticular activating system (RAS)
component of the reticular formation in the midbrain important for alertness and attentiveness
habituation
when the RAS modulates activity in the cerebral cortex so that it ignores repetitive, inconsequential stimuli
the reticular formation also has the following functions (2)
pain modulation, and sleep and consciousness
an injury here can cause an irreversible coma
reticular activating system
cerebellum
largest part of hindbrain; second-largest part of the brain as a whole; contains more than half of all brain neurons
granule cells
found in cerebellum; most abundant type of neuron in the entire brain
purkinje cells
large cerebellar neurons: axons project to deep nuclei to synapse with neurons that lead to the brainstem
the right and left _____ _____ are connected by a bridge called the _____
cerebellar hemispheres, vermis
folia
superficial cortex of grey matter with folds; cerebellum
abor vitae
branching white matter of the cerebellum
functions of the cerebellum (2)
- motor coordination and locomotor ability
- sensory, linguistic, emotional, and other non-motor functions
ataxia
clumsy, awkward gait
damage to what portion of the brain can cause ataxia?
cerebellum
diencephalon had three major components
- thalamus
- hypothalamus
- epithalamus
damage to what portion of the brain causes desynchronization between hemispheres and can lead to epilepsy/seizures?
thalamus
what does the thalamus do?
synchronizes electrical activity between the two cerebral hemispheres
thalamus: gateway to the cerebral cortex
- nearly all input to the cerebrum synapses in thalamic nuclei
- processes information on its way to the cerebral cortex
- not all info passes along; thalamus screens out most of the info it receives
thalamus: key role in motor control
- relays signals from the cerebellum to cerebrum
- provides feedback loops between cerebral cortex and basal nuclei
thalamus: involved in memory and emotion
limbic system includes some of the anterior thalamic nuclei
hypothalamus
forms part of the walls and floor of the third ventricle; extends anteriorly to the optic chiasm and extends posteriorly to mammillary bodies; processes olfactory and other sensory info and controls reflex eating movements
the hypothalamus attaches to the _____ _____ through a stalk-like structure called the _____
pituitary gland, infundibulum
the major control center of autonomic nervous system and endocrine system
hypothalamus
seven functions of the hypothalamic nuclei
- hormone secretion
- autonomic effects
- thermoregulation
- food and water intake
- sleep and circadian rhythms
- memory
- emotional behavior and sexual response
hypothalamic nuclei: hormone secretion
- controls anterior pituitary, thereby regulating growth, metabolism, reproduction, and stress responses
- produces posterior pituitary hormones for labor contractions, lactation, and water conservation
hypothalamic nuclei: autonomic effects
- major integrating center for autonomic nervous system
- influences heart rate, blood pressure, gastrointestinal secretions, mobility, etc.
hypothalamic nuclei: thermoregulation
hypothalamic thermostat monitors body temperature, activates mechanisms to adjust temperature if necessary
hypothalamic nuclei: food and water intake
- regulates hunger and satiety; responds to hormones influencing hunger, energy expenditure, and long term control of body mass
- osmoreceptors monitor osmolarity of the blood, and can stimulate production of antidiuretic hormone (ADH) to help conserve water
hypothalamic nuclei: sleep and circadian rhythms
suprachiasmatic nucleus controls 24-hour rhythm
hypothalamic nuclei: memory
mammillary nuclei relay signals from hippocampus to thalamus
hypothalamic nuclei: emotional behavior and sexual response
anger, aggression, fear, pleasure, contentment, sexual drive
pineal gland
an endocrine gland located in the epithalamus; produces/secretes the hormone melatonin which is important in the day/night cycle and reproductive function