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Virology > Lecture 8 > Flashcards

Lecture 8 Flashcards

1
Q

Where does pox virus assemble

A

In cytoplasm

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2
Q

Are poxviruses zoonotic

A

yes, in some domestic animals they can be

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3
Q

What doe all poxviruses cause

A

Skin lesions

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4
Q

Infection with what prevents smallpox

A

Cow pox

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5
Q

What does the viral core of poxvirus contain

A

RNA polymerase

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6
Q

What happens to viral proteins in pox virus before DNA replication

A

They are translated

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7
Q

Where are viral particles constructed in poxvirus

A

In cytoplasm within viral factories

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8
Q

In poxvirus, where is DNA replication occurring

A

In the cytoplasm

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9
Q

How is DNA replicated in poxvirus

A

as long concatemers

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10
Q

How can pox virus infect their host (3)

A
  1. Though skin by mechanical means
  2. Respiratory tract
  3. Oral route
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11
Q

What can poxvirus pathogenesis be (2)

A
  1. Localised

2. Systemic

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12
Q

Where does initial replication of poxvirus occur

A

At site of infection

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13
Q

How is poxvirus taken from lymph nodes to blood

A

via thoracic duct

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14
Q

What do Poxviruses target

A

Primary immune mediators

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15
Q

What form is poxvirus usually in

A

Cutaneous form

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16
Q

What form is poxvirus usually in canarys

A

Systemic form

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17
Q

In canaries what does the systemic disease present (2)

A
  1. Hepatic necrosis

2. Pulmonary nodules

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18
Q

What is the genus of fowlpox

A

Avipoxvirus

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19
Q

Occurrence of poxvirus

A

Worldwide

20
Q

What are the 2 forms of fowlpox

A
  1. Cutaneous form

2. Diphtheroid form

21
Q

What does the cutaneous form of fowlpox cause

A

Nodular lesions on the comb, wattle, eyelids, other non feathered areas

22
Q

What does the diphtheroid form of fowlpox cause

A

Nodules on mucosal membranes of pharynx, trachea, oesophagus

23
Q

How to diagnose fowlpox (4)

A
  1. Skin lesions
  2. Tracheal lesions
  3. Histopathology
  4. PCR
24
Q

How to control fowlpox

A
  1. Cell culture propagated vaccine can be used on day old chicks
  2. Avain embryo origin injection
25
Q

Where do lesions of caripoxvirus develop

A

Lungs and respiratory tract

26
Q

What type of disease are capripoxvirus know as

A

Transboundary disease

27
Q

How many serotypes exist of sheeppox and goatpox

A

1

28
Q

What economic importance do pox viruses have

A
  1. Can be fatal

2. Limit trade and export

29
Q

What does leporipoxvirus cause

A

Benign fibromas

30
Q

What happens to rabbits that survive leporipoxvirus (Myxoma virus)

A

Subcutaneous gelatinous swellings appeal all over the body

31
Q

How can parapoxvirus be distinguished morphologically

A

Narrower and have a more oval shape

32
Q

How long can the Orf virus live

A

Years

33
Q

Is the Orf virus zoonotic

A

Yes

34
Q

How to prevent parapoxvirus (2)

A
  1. Vaccinate

2. Disinfect equipment

35
Q

How long does it take to gain immunity with parapoxvirus after being vaccinated

A

2 weeks

36
Q

What does bovine parapoxvirus cause

A

Mild lesions on muzzle

37
Q

Where do adenoviridae viruses replicate

A

Nucleus

38
Q

What sort of infections are associated with adenoviruses

A
  1. Respiratory
  2. Eye
  3. GIT
39
Q

What does CAV-1 replicate

A

Vascular endothelial cels as well is a hepatic and renal parenchyma cells

40
Q

What are the majority of infections of CAV-1

A

Asymtomatic

41
Q

What is CAV-2 responsible for

A

Respiratory disease

42
Q

What diagnosis technique is used to identify the serology of CAV-1/2 (2)

A
  1. ELSIA

2. HAI

43
Q

How can you control CAV-1/2

A

Vaccine

44
Q

Hoe are FAdVs transmitted

A

Horizontally as well as vertically

45
Q

How do you control IBH in broilers

A

Vaccinating breeding birds

46
Q

How are broilers protected from IBH

A

they have maternal antibodies

Virology (23 decks)

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