Lecture 16 Flashcards
What are the subfamilies of Herpesviridae (3)
- Alphaherpesvirinae
- Betaherpervirinae
- Gammahepesvirinae
Where is Equid alphaherpesvirus 1 and 4
In horses
What does EHV-1 cause
respiratory disease, abortion and neurologic disease
What does EHV-4 cause
Respiratory disease
Where is EHV-1 and -4 most commonly seen
Weaned foals and yearlings
Clinical signs of EHV-1 and -4
Coughing, nasal discharge, enlargement of the mandibular and/or retropharyngeal lymph nodes, lethargy, anorexia, conjunctivitis
Clinical signs of EHM (5)
- Incoordination of hind
- Ataxia
- Urine retention
- Recumbency
- Neurological sigs are preceded by fever and/or respiration
How to diagnose EHV-1 and -4 (3)
- Laboratory diagnosis with histological lesions
- Viral antigens
- Viral genome can be detected using specific PCR
What are the vaccines of EHV-1 and EHV-4 (2)
- Live attenuated and inactivated vaccines
2. Reduce abortion and CNS infection
Equid gammeherpesvirus 2 and 5 is present where?
Horses
What is associated with Equine Multinodular Pulmonary Fibrosis
EHV-5 and with EHV-2, can be linked with a characteristic interstitial lung fibrosis
What does Equine Multinodular Pulmonary Fibrosis affect
Older horses causing weightless and reduced ability to exercise as result of the formations of nodular lesions in the lungs
Where does Equid alphaherpesvirus cause lesions
Penis and vulva
What are the clinical signs of canid alphaherpesvirus 1 in pups
Generalised necrotising and haemorrhage disease
How can pups become infected with canid alphaherpesvirus
Neonatal, this causes vocalisation, anorexia, dyspnoea, abdominal pain, incoordination and soft faeces