Lecture 1 Flashcards
What is a virus
Smallest infectious agents and scrapie
What does a virus consist of
1 or more molecules of only one type of nucleic acid - protective protein shell
What are some viruses enclosed within
An envelope that contains both protein and lipid
What are the characteristics of viruses (3)
- They are all obligate intracellular parasites
- Unique way of replication
- Programs the infected cell
What is a virus structure
(refer to lecture notes)
What viruses have helical symmetry
Rhabdoviruses
What viruses have complex symmetry
Large viruses
- Poxviruses
How can viruses mature
Budding though a membrane and acquiring a lipid envelope of host origin
What are embedded in a viral envelope
Glycoproteins
What does viral nucleic acid play a vital role in
Replication
What are viral proteins
A structural/non-structural protein. Structural proteins are those that can be incorporated into virison
Function of viral proteins (structural) (4)
- Protect viral gnome
- Assist in the attachment of virus particles to a susceptible host cell
- Acts as immunological antigens
- Give structural symmetry
Function of non-structural viral proteins
- Enzymes form replication cycle and enzymes such as reverse transcriptase
What is an Arbovirus
Arthropod-borne virus
What are prions
The transmissible agent responsible for subacute spongiform encephalopathies
What do prions not include
Nucleic acid
What is capripoxvirus transmitted by
Ticks
Can viruses contain both RNA and DNA
No
What is a capsid
Protein membrane
What does the capsid protect
Nucleic acid
What virus have 2 concentric shells
Reoviridae
How many different morphology do viruses have
5
Where do viruses usually get their envelope
Membrane from the host cell
How does the virus escape the cell
Via budding
What are non-structural proteins
Enzymes
