Lecture 8

Question 1

Neoplasm

Answer 1

Abnormal mass of tissue, the growth of which exceeds ad is un-coordinated with that of normal tissues, and which persists in the same excessive manner after cessation of the stimuli which evoked the change.

Question 2

Neoplasia

Answer 2

The process by which a neoplasm is formes

Question 3

Tumour

Answer 3

Swelling

Question 4

Page’s disease of the nipple

Answer 4

Metastasis within the epithelium

Question 5

Particular sites of mets

Answer 5

Liver: GIT carcinomas, GUS, bronchus, breast
Lungs: Sarcoma, carcinoma of thyroid, breast, kidney, bronchus etc
Bone: Breast, thyroid, prostate, bronchus, uterus

Question 6

Terms

Answer 6

Adenoma= Benign, glandular
Papilloma= Benign, capillary like skin lesions
Cystadenoma= Benign, glandular element also cystic
Polyp= A mass attached to a surface which may or may not be a neoplasm
‘sarcoma’ = malignant
‘oma’ benign

Question 7

Carcinoma

Answer 7

Malignant tumour of epithelial tissue

Question 8

Sarcoma

Answer 8

Malignant tumour of stromal tissue

Question 9

Leukaemia

Answer 9

Neoplastic proliferation of haemopoetic stem cells. Neoplastic cells spill over into the blood stream. All regarded as malignant.

Question 10

Lymphoma

Answer 10

Malignant proliferation of cells of lymphoid tissue.

Hodgkins disease - REED-STERNBERG
Non-Hodgkins

Question 11

Teratoma

Answer 11

Arises from totipotential cells. Can occur in ovaries or prostate. Solid masses.

Question 12

Cachexia

Answer 12

Severe weight loss
Increased metabolic rate
Tumour necrosis factor etc

Question 13

Paraneoplastic syndromes

Answer 13

Carcinoma of branches -> Cushing’s syndrome (ADH)
Fibrosarcoma -> Hypoglycaemia
Renal carcinoma -> EPO
Pancreas and bronchus -> thrombophlebitis migrant (inflammation of blood vessels)