Lecture 12

Question 1

Chronic gastritis

Answer 1

Ongoing inflammation of the stomach mucosa
Can provide an environment for dysplasia and metaplasia
Symptoms include: Upper abdo pain, indigestion/bloating, N+V, belching, loss of appetite/weight loss
Causes: A,B,C and other

Question 2

H.pylori

Answer 2

Gram -ve bacterium in the stomach, particularly antrum.

Question 3

Peptic ulcers

Answer 3

Usually occurs in D1 or antrum
Associated with H. pylori and NSAIDs
Complications: bleeding, anemis, massivt haematemsis, perforation leading to peritonitis, long term cancer at edge of ulcer

Question 4

Oesophageal carcinoma

Answer 4

Squamous cell carcinoma
Adults over 45, M:F 4:1.

Adenocarcinoma
Linked with barrett’s oesophagus
M:F 7:1

Question 5

Adenocarcinoma stomach

Answer 5

90% gastric malignancies
2nd commonest malignancy worldwide
Early symptoms resemble gastritis

Question 6

Small bowel neoplasia

Answer 6

Relatively rare

Adeonocaricnoma, GI stromal tumour, lymphoma, carcinoid (neuroendocrine) tumour