Lecture 7

Question 1

Atheroma

Answer 1

Build up of fatty material on the inside wall of an artery

Question 2

Atherosclerosis

Answer 2

The progressive narrowing and hardening within an artery potentially resulting in a complete blockage

Question 3

Plaque formation

Answer 3

Activated platelet
Deposition of chemokine
Adhesion of monocytes
Monocytes migrate and transform into macrophages
Macrophages ingest LDL
Plaque formation (starts as fatty streak)

Question 4

Claudication

Answer 4

Cramping up of calf

Question 5

Risk factors for ischaemic heart disease

Answer 5

Male
Positive family history
Age
Genetic factors

Hyperlipidaemia, smoking, hypertension, diabetes, lack of exercise, obesity, heavy alcohol consuption

Question 6

NSTEMI

Answer 6

Partial blockage of major artery

Question 7

STEMI

Answer 7

Full blockage of major artery

Question 8

Cholesterol

Answer 8

HDL - Good. Metabolises cholesterol from tissues and transports it to the liver to be excreted as bile

LDL- Bad