lecture 7 antibacterial drugs Flashcards

1
Q

antimicrobial

A

a natural or synthetic chemical that kills or inhibits the growth of microorganisms

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2
Q

ideal antibacterial properties

A

no resistance
narrow spectrum of activity
bactericidal
selective

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3
Q

what do beta lactam antibiotics target

A

peptidoglycan

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4
Q

what can work on the cell wall of gram pos

A

glycopeptides

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5
Q

why cant glycopeptides work on gram neg

A

cell wall is too thick

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6
Q

eukaryotic ribosomes

A

80s

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7
Q

bacteria ribosomes

A

70s

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8
Q

examples of 30s inhibitors

A

aminoglycosides

tetracylines

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9
Q

aminoglycans are bacterio-

A

bactericidal

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10
Q

tetracylcines are bacterio

A

bacteriostatic

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11
Q

common feature of amnioglycans and tetracyclines

A

both can be taken up by eaukaryotes

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12
Q

what inhibits DNA synthesis

A

quinalones

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13
Q

quinalone administration

A

oral

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14
Q

what do rifamycins do

A

block mRNA synthesis

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15
Q

sulfonomides

A

inhibit synthesis of DHA

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