lecture 13 HIV and AIDS

Question 1

what membrane receptors are involved in HIV infection

Answer 1

CCR5 and CD4

Question 2

what are the essential components of HIV virus

Answer 2

two strands of RNA
reverse transcriptase
protease
integrase

Question 3

what binds to CCR5 and CD4

Answer 3

Gp120

Question 4

what does viral reverse transcriptase do

Answer 4

makes a viral copy of the DNA

Question 5

what puts the viral DNA into the host DNA

Answer 5

intergrase

Question 6

how is the new genome passed on

Answer 6

if the cell undergoes mitosis

Question 7

characteristic clinical feature of HIV

Answer 7

depleted CD4

Question 8

the mRNA is read into proteins, what happens next

Answer 8

protease cuts them into viral package

Question 9

where does the mature viral package assemble

Answer 9

cell membrane

Question 10

how is the mature viral package released?

Answer 10

budding

Question 11

what is the end pathway for infected cells

Answer 11

apoptosis

Question 12

what is karposis sarcoma

Answer 12

viral cancer - proliferation of blood vessels

Question 13

what is karposis sarcoma caused by

Answer 13

HBH8

Question 14

CMV affects

Answer 14

retina