lecture 15 parasitic infections Flashcards

1
Q

what kind of parasite is malaria

A

protozoan

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2
Q

what are the two main types of parasite

A

helminth and protozoan

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3
Q

what are helminths and protozoa …karyote

A

eukaryotes

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4
Q

how many cells do protozoa

A

unicellular

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5
Q

what are helminths

A

worms

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6
Q

what do helminths produce to reproduce

A

eggs

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7
Q

what might it be hard to find drugs for parasites

A

they are also eukaryotes

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8
Q

what is the drug target for helminths

A

neuromuscular system

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9
Q

what happens when the trugs target the helmiinths

A

paralysis

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10
Q

why are the current anitmalarials becoming ineffective

A

resistance

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11
Q

vector for malaria

A

anopheles

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12
Q

in malaria where does the parasite affect

A

liver and blood

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13
Q

how does the parasite get from mosquito to human

A

bites

injects sporozites

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14
Q

where do the sporozoites first go

A

the liver

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15
Q

how long do the sporozoites remain in the liver

A

10 days

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16
Q

what do they do in the liver

A

mature to form schizonts

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17
Q

what do the schizonts form

A

merozoites

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18
Q

how do the merozoites get into the blood

A

make the liver cell they are in burst

19
Q

in the blood what do the merozoites mature into

A

trophozoites

20
Q

where does sexual reproduction occur in the mosquito

21
Q

what does the zygots in the mosquitos stomach form

A

it matures into ookinete

22
Q

what does oopinete do

A

moves from stomach to midgut and here produces sporozoites which go to the salivary glands

23
Q

when do you start feeling sick if you have malaria

A

when it gets into the blood

24
Q

where do mosquitos undergo asexual reproduction in the human

A

blood cells

25
how long is the peak of fever in malaria
4 days
26
what are the three big groups of malaria chemo
quinolines antifolates artemisinin
27
how does chloroquine work
blocks the parasite detoxification of heme
28
how do antifolate drugs work
affect folic acid metabolism of the parasite
29
what is sleeping sickness also known as
African trypanosomiasis
30
what type of parasite is African trypanosomiasis
protozoan
31
what is the vector for African trypanosomiasis
tsetse fly
32
what can the African trypanosomiasis cross
blood brain barrier
33
what kind of problems do African trypanosomiasis cause
neurological
34
South american trypanosomiasis is also called
chagas disease
35
what is the vector for south american trypanosomiasis
triatomine insects
36
what part of the body do triatomone insects tend to bite
the face
37
what is Leishmaniasis transmitted by
female sandflies
38
what does Leishmaniasis do
invades macrophages
39
who does toxoplasmosis affect
the immunocompramised
40
what does toxoplasmosis cause
mild lymphadenopathy
41
giardiasis is
diarrheal disease
42
how does prazinquantel work
paralyses the worms
43
where does ascariasis live
intestines