Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

block 9 anna > lecture 16 general cancer > Flashcards

lecture 16 general cancer Flashcards

1
Q

what are the two types of regulatory genes that lead to cancer

A

proto-oncogenes

tumour supressor genes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what happens to proto-oncogenes

A

they are mutted and become oncogenes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what do oncogenes do

A

drive proliferation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what do tumour supressor gene usually control

A

DNA repair

cell death

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what is EGFR

A

gene expressed all around the body

receptor for tyrosine kinase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what happens if EGFR is constantly active

A

drives cell proliferation

cell survival through apoptosis inhibition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what is a tumour suppressor gene

A

any gene which supresses cell growth

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what is li fraumeni syndrome

A

heterozygous loss of p53

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

example of a main tumour suppressor gene

A

p53

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

example of inhierited cancer geene

A

BRCA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what does a mutation in the BRCA gene cause

A

breast cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what type of gene is the APC gene

A

oncogene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what does a mutation of the APC gene cause

A

adenomas in the colon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what cancer can asbestos cause

A

mesothelioma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

human papilloma virus

A

oncogenic

DNA virus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

helicobacter pilori is gram

A

egative

17
Q

metaplasia

A

transformation of one mature cell into another

18
Q

how can acid reflux be linked to cancer

A

can cause metaplasia in the oesophagus

19
Q

why do cancers want blood supply

A

to spread

20
Q

whats an adenoma

A

benign neoplasm of cells

21
Q

what is a carcinoma

A

malignant epithelium neoplasm

22
Q

what type of carcinoma does glandular epithelium cause

A

adenocarcinoma

23
Q

what do connective tissue malignant tumours end in

A

sarcoma

24
Q

teratoma

A

cantains all three egerm layers

25
Q

where do lymphoid malignancies originate

A

B, T and NK cells

26
Q

circulating celltumours

A

leukimia

27
Q

lymphoma

A

cancers with a tumour mass

28
Q

what do benign tumours usually have surrounding them

A

fibrous capsule

29
Q

whats is transcoelomic

A

spreading through tissue

30
Q

what is tumour staging to do with

A

spread of the tumour

31
Q

unpredictable effects of tumours

A

paraneoplastic

block 9 anna (21 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions