Lecture 6 Unit 1 Flashcards
how do oxygen and nutrients move out of the blood?
by crossing the capillary wall and entering the interstitial fluid (ISF)
how do carbon dioxide and metabolic waste products move?
in the opposite direction
how long would body capillaries be if they were placed end to end?
60,000 miles and cross sectional area would be 5,000 cm^2
how long is the average capillary? and the lumen diameter?
capillary- 1 mm
lumen- 8 micrometers
what is the blow flow velocity in a capillary?
0.1 cm/sec
what is the concentration or density of capillaries in a given tissue proportional to?
the tissue’s metabolic activity
what does the term capillary bed refer to?
a network of capillaries where exchange of materials with the tissue cells can take place
how far is every cell tissue usually from a capillary?
~1.3 cell diameters
when is diffusion efficient?
only when diffusion distances are short
how do most substances move?
by diffusion
what can cross intercellular clefts?
pores, water and most small substances cross the capillary wall by diffusion through these pores
what can cross endothelial cell membranes?
some small molecules and gases can diffuse or be transported across the endothelial cell layer
what can cross fenestrations?
large molecules can pass easily through the fenestrations
what are the 3 routes for capillary exchange?
- intercellular clefts
- endothelial cell membranes
- fenestrations
where are continuous capillaries found?
found in lungs, skeletal muscle, and connective tissue