Lecture 22 Unit 3 Flashcards

1
Q

where does the hypothalamus receive input from

A

cortex, thalamus, limbic system and internal organs

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2
Q

what does the hypothalamus do

A

provides a link between the external and internal environment and the endocrine system

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3
Q

what do the hypothalamus and pituitary work together to do

A

control almost all aspects of growth, development, metabolism, and homeostasis

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4
Q

how does the hypothalamus control the pituitary gland

A

with special hormones called releasing hormones and inhibiting hormones

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5
Q

how does the hypothalamus release other hormones directly into circulation

A

through the posterior pituitary

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6
Q

how does the hypothalamus make use of the nervous system

A

it may send motor impulses to various tissue effectors

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7
Q

how does the hypothalamus make use of the endocrine system

A

uses it as an effector by secreting releasing and/or inhibiting hormones

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8
Q

what do releasing and inhibiting hormones act on

A

target cells in the anterior pituitary

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9
Q

what do the 5 types of anterior pituitary cells release into circulation

A

7 tropic hormones

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10
Q

how many releasing/inhibiting hormones are there

A

about 7

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11
Q

what are the 5 main cell types of the anterior pituitary gland

A
  1. somatotrophs
  2. thyrotrophs
  3. lactotrophs
  4. gonadotrophs
  5. corticotrophs
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12
Q

what do somatotrophs do

A

secrete human growth hormone

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13
Q

what do thyrotrophs do

A

secrete thyroid stimulating hormone

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14
Q

what do lactotrophs do

A

secrete prolactin

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15
Q

what do gonadotrophs do

A

secrete follicle stimulating hormone and lutenizing hormone

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16
Q

what do corticotrophs do

A

secrete adrenocorticotropic hormone and melanocyte stimulating hormone

17
Q

what does growth hormone releasing hormone regulate

18
Q

what does growth hormone inhibiting hormone regulate

A

HGH or TSH

19
Q

what does gonadotropin releasing hormone regulate

A

lutenizing hormone and follicle stimulating hormone

20
Q

what does prolactin releasing hormone regulate

21
Q

what does prolactin inhibiting hormone regulate

A

prolactin or melanocyte stimulating hormone

22
Q

what does corticotropin releasing hormone regulate

A

ACTH and MSH

23
Q

what does thyrotropin releasing hormone stimulate

24
Q

what does HGH do within target cells

A

increases synthesis of insulin like growth factors that act locally or enter blood stream

25
what do insulin like growth factors do
- increase cell growth and cell division by increasing the uptake of amino acids and synthesis of proteins - stimulate lipolysis in adipose tissue - decrease glucose use by most body cells so blood glucose levels remain high enough to supply the brain
26
what are some stimuli for GHRH
hypoglycemia, deep sleep, decreased fatty acids and increase amino acids in blood, increased sympathetic stimulation
27
what are some stimuli for GHIH
hyperglycemia, REM sleep, increased fatty acids and decreased amino acids in blood, obesity, low levels of thyroid hormones, high levels of hGH
28
what does FSH do in females
stimulates secretion of estrogen and initiates the formation of follicles within the ovary
29
what does FSH do in males
stimulate sperm production in testes
30
what does LH do in females
- secretion of estrogen and progesterone - ovulation - formation of corpus luteum
31
what does LH do in males
secretion of testosterone
32
what does prolactin cause
milk production during suckling
33
what inhibits MSH release
PIH (dopamine)
34
what does ACTH stimulate
release of cortisol from adrenal cortex
35
what is ACTH release stimulated by?
hypoglycemia, physical trauma, and IL-1
36
what does cortisol do
inhibits the release of CRH and ACTH
37
what does TSH do
- stimulates the synthesis and secretion of T3 and T4 | - stimulate metabolic rate