Lecture 24 Unit 4 Flashcards
1
Q
what is the major human glucocorticoid
A
cortisol
2
Q
what is the function of cortisol
A
- increase rate of protein catabolism
- promote gluconeogenesis
- provide resistance to stress by making nutrients available
3
Q
what do glucococorticoids do
A
raise blood pressure by increasing sensitivity of blood vessels to other hormones which cause vasoconstriction
4
Q
how are glucocorticoids anti-inflammatory and immunosuppressive
A
- by reducing release of histamine from mast cells
- by decreasing capillary permeability
- by depressing phagocytosis
- by inhibits white blood cells
5
Q
what causes type 1 diabetes? type 2?
A
1-deficiency of insulin
2-insulin sensitivity
6
Q
where do target cells for ACTH secrete glucocorticoids, mainly cortisol
A
zona fasciculata
