Lecture 6 Flashcards

1
Q

What oxygen use class is Strep Pyogenes found in?

A

Strep Pyogenes is a MicroAeroPhilic bacterium

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2
Q

Can Strep use Oxygen?

A

NO, MicroAeroPhilic=no Resp!!

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3
Q

What does the word Pyogenic mean?

A

Pyogenic= “Pus Forming”

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4
Q

What does a decorated crab have to do with Strep pyogenes?

A

It can disguise itself from our immune sys

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5
Q

What is the END result of superantigen of Strep Pyogenes?

A

Scarlet Fever

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6
Q

What is another name for enzymes secreted by both strep and staph causing cellulitis?

A

F.E.B.!!! Flesh Eating Bacteria

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7
Q

What are the three ways we can classify a Strep member?

A

1.Hemolysis (beta, alpha, gamma) 2.Its Lancefield CHO Antigens (A,B) 3. Its Natural Clusters/loactions

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8
Q

What is the beta-hemolytic strep’s affect on RBCs?

A

COMPLETE hemolysis

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9
Q

What is the alpha-hemolytic streps affect on RBCs?

A

Changes Hemoglobin shape and therefore changes its color to GREEN!

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10
Q

What is the gamma-hemolytic strep affect on an RBC?

A

NOTHING!

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11
Q

S. Lactis =

A

Lactics Strep

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12
Q

E. Fecalis, E. Faecium, E. Bovis, E. Swis=

A

Enterococci Strep

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13
Q

S. Pyogenes, S. Agalactiae, S. Pneumonia=

A

Pyogenic Strep

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14
Q

S. Mitis, S. Salivarius, S. Mutans=

A

Viridans Strep

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15
Q

What are the MAJOR bacterial species found in the oral cavity?

A

alpha-hemolytic viridans strep

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16
Q

What is G.A.S. (group-a-strep), has many toxins, and causes step throat, rheumatic fever, cellulitis, and scarlet fever?

A

Strep Pyogenes

17
Q

What is Beta-hemolytic, has a Capsule, and causes neonatal sepsis (birth canal flora)? (hint: battle star galactitca)

A

S. Agalactiae

18
Q

What is alpha-hemolytic, has a capsule, and causes MENINGITIS, pneumonia, and ear infections?

A

S. Pneumoniae

19
Q

What is alpha-hemolytic and can cause SUB-acute endocarditis, caries?

A

Viridans strep

20
Q

Which hypersensitivity type is most serious?

A

Type I

21
Q

How would repeated Strep occur?

A

The M protein presented by Strep becomes altered

22
Q

What are cyclic toxins produced by strep that can kill leukocytes?

A

Strepto-Lysin

23
Q

How can strep INACTIVATE the C5a “911” molecule?

A

Using C5a peptidase

24
Q

What are the THREE approaches for strep to damage the host?

A

1.Pyogenic Infection 2.Toxic Systemic 3.Immune Sequelae Disease

25
Q

What is the skin manifestation of BOTH Strep AND Staph pyogenic infection?

A

Impetigo

26
Q

What are the three main strep pyogenic/LOCAL infections?

A

Strep Throat, Impetigo, and Cellulitis

27
Q

What are the two main toxic systemic diseases of strep?

A

Scarlet Fever and Strep Toxic Shock Syndrome (STSS)

28
Q

What are the two main Sequelae diseases of strep? What are their sensitivity types?

A

Rheumatic Fever (Type II), and Glomerulonephritis (Type III)

29
Q

Which of the three exotoxin classes is at the root of Scarlet Fever and Strep Toxic Shock-LIKE Syndrome? (end result is a cytokine storm)

A

Superantigen! (Toxin “glues” TCR’s to Class II MHCs)

30
Q

Which Type of hypersensativiy has to do with the coke bottle and the water bottle looking similar and therefore the body mounts a response agains both pathogen and self receptors?

A

Type II…..Think Two bottles!

31
Q

What type of hypersensitivity is caused by the formation of complexes that can gather “like leaves on the storm drain during the fall?” (which then macrophages come and indescriminantly eat)

A

Type III…Think Fall is the third season

32
Q

Which is generally more resistant to antibiotics: strep or staph?

A

Staph is generally more resisstant

33
Q

NO CARDS ON ACUTE VS SUBACUTE

A

MAKE SOME LATER?