Lecture 12 AB toxin usin' Gram + RODS, spores

Question 1

How do they fight Diphtheria?

Answer 1

TOXOID vaccine (alter the antibody a bit)

Question 2

Does diphtheria use spores?

Answer 2

NO

Question 3

What is the exotoxin used by Diphtheria? What is the main target tissue?

Answer 3

A-B Exotoxin- SYSTEMIC

Question 4

What is the spore coat made of?

Answer 4

Keratin (finger nails!)

Question 5

What is the massive cell wall made of in a spore?

Answer 5

TONS of poorly linked Peptidoglycan

Question 6

What bacteria causes Gas Gangrene? and Food Poisioning?

Answer 6

Clostridium Perfringens

Question 7

What bacteria causes Antibiotic colitis?

Answer 7

Clostridium Difficile

Question 8

What do C. Botulinum and C. Tetani AB exotoxins target?

Answer 8

NERVOUS TISSUE

Question 9

How does C. Tetani AB toxin work?

Answer 9

Blocks Glycene release from inhibitory neuron

Question 10

How does C. Botulinum toxin work?

Answer 10

Blocks Acth Release from main neuron

Question 11

What alters the normal flora of the gut to cause pseudomembranous colitis?

Answer 11

Clostridium Difficile

Question 12

What are the three human infections of B. Anthracis? What is the most serious?

Answer 12

1. Cutaneous 2.Pulmonary–MOST SERIOUS 3.GastroIntestinal

Question 13

How did the baby Mammoth die?

Answer 13

B. Anthracis