Lecture 13-TEEEBEEE Flashcards
What was TB called when Doc Holladay had it?
Consumption
What is 99% of transmission of Mycobacterium?
Man to man…very little thru cows and birds if HIV present
What is unique about the structure of mycobacterium?
HIGH lipid (WAXY coat)
What oxygen use category does mycobacterium fall under?
Obligate Aerobe (MAKES SENSE!)
Does Mycobacterium grow slowly or quickly?
SLOWLY 4-6 wk colonies
How much of the world has been infected with TB? How many people were infected in the 19th century?
1/3! BOOM…100% infection in the 19th century
What is the name of the wax that makes up mycobacterium’s coat?
MYCOlic Acid (GET IT?)
Where does M. Leprae thrive in the human body?
the COLD parts (limbs, what not)
What cell type does TB attack?
Macrophages
How do you stain mycobacterium?
Acid-Fast YO!
What does therapy do for both Mycobacteria Leprasy? Two kinds..
Tuberculoid–STRONG IMMUNE RESPONSE progression takes DECADES…Lepromatus—LESS IMMUNE RESPONSE progression takes YEARS
How do you test for Lepracy on the skin?
Feather test
Do antibodies work for TB?
NO, look to vaccinate or treat with long term antibiotics
