Lecture 14- VIROLOGY! Flashcards
What is an example of a lytic, acute viral replication?
Naked Viruses use this method!
What is an example of non lytic, chronic viral replication?
Enveloped viruses Modus Opperandi
What is an example of Latent viral replication?
HERPES!
What is an example of viral replication via transformation?
HPV (cancer)
What are the envelope possibilities for dsRNA viruses?
JUST NAKED!
What are the envelope possibilities for ssRNA viruses?
Naked and Enveloped
What are the envelope possibilities for dsDNA viruses?
Naked and Enveloped
What are the envelope possibilities for ssDNA viruses?
JUST NAKED!
What does (+) “sense” orientation infer?
That it is in the same orientation as normal mRNA
What structure determines what cells a virus can infect?
Spike Proteins!
What type of mRNA MUST viruses be able to produce in order to replicate their protein products?
(+) “sense” RNA, some viruses come like this already, some have to bring an enzyme that will translate to this
BIG concept: what does (-)ssRNA need in order to convert it to (+)ssRNA?
It needs RNA-dependent RNA polymerase
What is another name for Reverse Transcriptase?
RNA-dependent DNA Polymerase
What is the difference between horizontal and vertical transmission?
Horizontal: person to person, Verticle: mom to neonate
What it the iceberg effect?
When a pathogen (virus) is asymptomatic and therefore people can be carriers and not know it. So a large amount of a population is infected, but you can’t tell
What is an example of an iceberg effect virus?
PolioMyelitis…HUGE infection rate, but only 1% showed the paralyzed manifestation of the disease
Does a ssDNA virus need to 1.code for a polymerase? 2. bring its own polymerase?
1.NO 2.NO
Does a dsDNA virus need to 1.code for a polymerase? 2. bring its own polymerase?
1.NO 2.NO
Does a (+) ssRNA virus need to 1.code for a polymerase? 2. bring its own polymerase?
1.YES (needs a code to make an RNA-dependent, RNA polymerase) 2.NO
Does a (-) ssRNA virus need to 1.code for a polymerase? 2. bring its own polymerase?
1.YES (needs to code to make an RNA-dependent, RNA polymerase) 2.YES (needs to bring in a converter from (-)ssRNA to (+)ssRNA
Does a dsRNA virus need to 1.code for a polymerase? 2. bring its own polymerase?
1.YES 2.YES
