LECTURE 10 NEISSERIA Flashcards
What are the two main Neisseria bugs?
Nei-ss-er-ia Men-ingit-ides & Neisseria Gon-or-rh-oe-ae
Why are Neisseria the official bacteria of Starbucks? (What is their structure?)
Two Gram - Cocci (diplocci) pressed together making a flat side on each. LOOK like coffee beans!
What is the name of the N. Meningitides when it is in unharmful in the back of the throat?
Meningococcus
What is the name of the N. Meningitides when it becomes an infection in the blood (sepsis)? (NO BUENO!)
MeningococcEMIA
What are the 4 major virulence factors of N. meningitidis?
1.Fimbriae 2.Capsule 3.IgA Protease 4.Blebs of LPS
Who are carriers of N. Meningitides? How is it transmitted?
Humans…respiratory droplets in close quarters
When was the little blip on the N. Meningitides graph of when to catch it?
18-21 yr olds… Partying and swapping spit
Which bacterium has the ‘bleb’?
Neisseria Meningitides
How do we combat Neisseria Meningitides?
Vaccine (does not work in kids) and prophylaxsis
What are the three Bacteria that can cause Meningitis?
1.STREP PNEUMONIAE (G+) 2. H. Influenza (G-) 3. N. Meningitides (G-)
What is the oxygen use classification for N. Meningitides and N. Gonorrhoeae?
Aerobic & MicroAeroPhillic
What percent of people become infected with N. Meningitides (meningococcus)?
99%!!!!! therefore 1% get the disease
What is the iceberg effect in relation to N. Meningitides?
99% of people are infected and can pass it along. A nightmare for public health concerns
How long does it take to die from MeningoCoccemia?
6-8 hours! BOOM!
What are the 4 MAIN virulence factors for N. Gonorrhoeae?
1.Antigen Variation (camo) 2. Hide Inside the cell 3.IgA Protease 4.B-Lacamase! (penicillin resistant)
What are two reasons for N. Gonorrhoeae being a larger problem in women then men?
1.Easier to catch (Surface Area of Vagina epithelium) 2. Less symptomatic then men
What is the worst case senario end disease of a N. Gonorrhoeae infection?
P.I.D. pelvic inflammatory disease
What is a common CO-INFECTION w/ N. Gonorrhoeae?
Chlamydia + Gonorrhoeae!!! WOOO!!
Can you get gonnorrhoeae from a toilet seat?
NO, its a very frail bacterium out in the open
What is the physical manifestation of N. Gonorrhoeae?
Pyogenic Lesions
Is N. Gonorrhoeae a local or systemic LPS problem?
Local LPS
Say a female makes it past PID and is still fertile and has a baby.. What can happen to that baby during birth if N. Gonorhoeae is present?
Newborn blindness
What is the number 1 cause for female abdominal surgery, sterility, and ectopic pregnancy?
Pelvic Inflammatory Diease PID YO!
