LECTURE 10 NEISSERIA

Question 1

What are the two main Neisseria bugs?

Answer 1

Nei-ss-er-ia Men-ingit-ides & Neisseria Gon-or-rh-oe-ae

Question 2

Why are Neisseria the official bacteria of Starbucks? (What is their structure?)

Answer 2

Two Gram - Cocci (diplocci) pressed together making a flat side on each. LOOK like coffee beans!

Question 3

What is the name of the N. Meningitides when it is in unharmful in the back of the throat?

Answer 3

Meningococcus

Question 4

What is the name of the N. Meningitides when it becomes an infection in the blood (sepsis)? (NO BUENO!)

Answer 4

MeningococcEMIA

Question 5

What are the 4 major virulence factors of N. meningitidis?

Answer 5

1.Fimbriae 2.Capsule 3.IgA Protease 4.Blebs of LPS

Question 6

Who are carriers of N. Meningitides? How is it transmitted?

Answer 6

Humans…respiratory droplets in close quarters

Question 7

When was the little blip on the N. Meningitides graph of when to catch it?

Answer 7

18-21 yr olds… Partying and swapping spit

Question 8

Which bacterium has the ‘bleb’?

Answer 8

Neisseria Meningitides

Question 9

How do we combat Neisseria Meningitides?

Answer 9

Vaccine (does not work in kids) and prophylaxsis

Question 10

What are the three Bacteria that can cause Meningitis?

Answer 10

1.STREP PNEUMONIAE (G+) 2. H. Influenza (G-) 3. N. Meningitides (G-)

Question 11

What is the oxygen use classification for N. Meningitides and N. Gonorrhoeae?

Answer 11

Aerobic & MicroAeroPhillic

Question 12

What percent of people become infected with N. Meningitides (meningococcus)?

Answer 12

99%!!!!! therefore 1% get the disease

Question 13

What is the iceberg effect in relation to N. Meningitides?

Answer 13

99% of people are infected and can pass it along. A nightmare for public health concerns

Question 14

How long does it take to die from MeningoCoccemia?

Answer 14

6-8 hours! BOOM!

Question 15

What are the 4 MAIN virulence factors for N. Gonorrhoeae?

Answer 15

1.Antigen Variation (camo) 2. Hide Inside the cell 3.IgA Protease 4.B-Lacamase! (penicillin resistant)

Question 16

What are two reasons for N. Gonorrhoeae being a larger problem in women then men?

Answer 16

1.Easier to catch (Surface Area of Vagina epithelium) 2. Less symptomatic then men

Question 17

What is the worst case senario end disease of a N. Gonorrhoeae infection?

Answer 17

P.I.D. pelvic inflammatory disease

Question 18

What is a common CO-INFECTION w/ N. Gonorrhoeae?

Answer 18

Chlamydia + Gonorrhoeae!!! WOOO!!

Question 19

Can you get gonnorrhoeae from a toilet seat?

Answer 19

NO, its a very frail bacterium out in the open

Question 20

What is the physical manifestation of N. Gonorrhoeae?

Answer 20

Pyogenic Lesions

Question 21

Is N. Gonorrhoeae a local or systemic LPS problem?

Answer 21

Local LPS

Question 22

Say a female makes it past PID and is still fertile and has a baby.. What can happen to that baby during birth if N. Gonorhoeae is present?

Answer 22

Newborn blindness

Question 23

What is the number 1 cause for female abdominal surgery, sterility, and ectopic pregnancy?

Answer 23

Pelvic Inflammatory Diease PID YO!