LEcture 3

Question 1

What antibody response is not long lived?

Answer 1

IgM

Question 2

Primary immune response, requires ________ post first exposure.

Answer 2

day/weeks

Question 3

Period of time that you have a pathogen but no antibodies to defend against it.

Answer 3

Viral window, (infected with no antibodies to help) (innate can act though)

Question 4

Why is HIV so devastating?

Answer 4

it takes out the traffic cop (CD-4 cells)

Question 5

B cells do not make antibodies until they become ________ cells

Answer 5

Plasma

Question 6

What type of reaction is an allergic reaction?

Answer 6

type 2, it can happen in minutes (IgE)

Question 7

Secondary immune response- subsequent exposures requires _______ (length of time) to occur.

Answer 7

hours-days

Question 8

Can an allergic response happen at first exposure?

Answer 8

no, it has to be at secondary exposure

Question 9

Secondary response we see almost totally _____.

Answer 9

IgG

Question 10

IN primary response we see some ____ and ____.

Answer 10

IgM and IgG

Question 11

The body is actively mounting an immune response by producing antibodies. Requires exposure to infectious agent (antigen)

Answer 11

Active immunity

Question 12

What part of active immunity is from an immunization with altered agent or its antigens?

Answer 12

Artificial

Question 13

True/False: If you hear the word immunization or vaccination you can’t determine if its active or passive immunity until you know what they were immunized with.

Answer 13

True

Question 14

What is where subject receives exogenous antibodies, (does not confer long-term immunity)

Answer 14

Passive immunity

Question 15

Why would you give artificial passive to a patient?

Answer 15

When you need immediate protection. (Like anti venom.) (Antibody from a horse) (Hep B immunoglobulin- don’t have time for you to produce your own antibodies) (rabies- series of shots with antigens and antibodies, because 0% chance of survival with rabies) so you want short term and long term help

Question 16

What are 3 hazards of immunity?

Answer 16

Inadvertent injury to the host
Development of autoimmunity
Hypersensitivity reactions

Question 17

What are some body sites and tissues that are immune privileged?

Answer 17

Eye: cornea, anterior chamber, vitreous, lens, pigment epithelium, retina.
Brain
Placenta
Ovary
Testis

Question 18

Can any antibodies get across the placenta?

Answer 18

IgG

Question 19

Every response in the body goes from what class switch?

Answer 19

IgM to IgG

only exception is with blood type

Question 20

What does ACID stand for with hypersensitivity reactions?

Answer 20

All are secondary immune responses:
I- Allergy/Immediate
II- Cell-bound/Cytotoxic
III- Immune Complex
IV- Delayed

Question 21

Hypersensitivity reaction of allergy? only hypersensitivity mediated by IgE

Answer 21

Type 1