Antibodies

Question 1

Macrophages connec to what tail?

Answer 1

Fc tail

Question 2

Where do antigens bind?

Answer 2

Fab

Question 3

What is a large y shaped glycoprotein?

Answer 3

Antibodies

Question 4

Antibodies are produced by ______.

Answer 4

B-cells

Question 5

An antibody will be either _____ or ______.

Answer 5

Kappa or Lambda

Question 6

This regulates cellular immunity.

Answer 6

TH1

Question 7

This regulates humoral immunity.

Answer 7

TH2

Question 8

________ bond is what holds the light chains together.

Answer 8

Disulfide

Question 9

__ is the only antibody to cross the placenta via Fcgamma receptors.

Answer 9

IgG

Question 10

___ and __ fix complement.

Answer 10

IgG and IgM

Question 11

This antibody has pentamers or monomers structure. First Ig to be made in fetus, first to be made by virgin Ag-stimulated B-cells

Answer 11

IgM= primary immune response

Question 12

What is the difference between plasma and serum?

Answer 12

Serum has used up the clotting factors.

Question 13

Does IgA fix complement?

Answer 13

no, because IgA is on our mucus membrane we don’t want inflammation to occur there. (in our gut)

Question 14

This is the major class of Ig in secretions, important in mucosal immunity.

Answer 14

IgA

Question 15

This is found on B cell surfaces and can bind to Antigens.

Answer 15

IgD

Question 16

Is a B-cell an antigen presenting cell?

Answer 16

Yes, B-cells produce antibodies. So, they are technically an antigen presenting cells.

Question 17

All mast cells are located in ______.

Answer 17

Tissues

Question 18

This antibody is least common Ig in plasma. Binds tightly to FcE receptors on basophils and mast cells.

Answer 18

IgE

Question 19

What happens to BP when you have a lot of histamine in the system?

Answer 19

Blood pressure plummets

Question 20

What is involved in allergic reactions

Answer 20

FcE receptors and mast cells

Question 21

What is involved in parasitic infections

Answer 21

IgE and Eosinophils

Question 22

What is unique to each class?

Answer 22

Heavy chains

Question 23

IgE (from previous exposure) is docked on ________

Answer 23

Mast cells

Question 24

We are infected but have not started to make antibodies.

Answer 24

Viral window

Question 25

WIth HIV it is not very __________ so you could see someone in the viral window for up to 6 months.

Answer 25

immunogenic

Someone could be tested and not have antibodies, but they could still have it.

Question 26

What immunity is where subject actively produces their own antibodies. Requires exposure to infectious agent.

Answer 26

Active

• Natural infection
• Artificial= immunization with altered agent or it’s antigens

Question 27

An immunization can be ____ or _______. What did you get immunized with?

Answer 27

active or passive

Question 28

What is another name for antibodies?

Answer 28

immune globulins

Question 29

What immuity is where subject receives exogenous antibodies. Does not confer long term immunity.

Answer 29

Passive

• Natural= Mother-child (IgG-placenta, IgA- breast milk)
• Artificial= Immunization with antibodies

Question 30

This immunity is not immediate but is long lived.

Answer 30

Active immunity

Question 31

What immunity is immediate but short-lived. Natural maternal antibodies (IgG) crosses placenta.
Artificial= immune globulins
Antivenom/Antitoxin

Answer 31

Passive

Question 32

If he gives a question about immunity, read on to see if it is active or passive.

Answer 32

do it