Lecture 2 Flashcards

1
Q

What is the distinction between amide and peptide bonds?

A

Not every amide bone is a peptide bond but every peptide bond is an amide bond. A peptide bond is an amide bond that is specifically used in the formation of polypeptides. Basically a peptide bond is a type of amide bond

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2
Q

Why is water so important?

A

Because it is the environment in which we find every biological molecule

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3
Q

Where does water’s special properties come from?

A

The difference in electronegativity between oxygen and hydrogen atoms

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4
Q

What is the shape of water molecules?

A

It has a tetrahedral position

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5
Q

How many lone pairs does a water molecule have?

A

2 pairs of lone pairs

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6
Q

What does the net dipole of water molecules allow?

A

It allows water to form hydrogen bonds with other water molecules

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7
Q

What is Hydrogen Bonding?

A

When one hydrogen is being shared by two electronegative atoms

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8
Q

What is the Hydrogen in the hydrogen bond donor attracted to?

A

The lone pair of the oxygen on the water molecule

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9
Q

What is the relative strength between hydrogen bonds and covalent bonds?

A

Hydrogen bonds are weaker than covalent bonds

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10
Q

How many hydrogen bond interactions can be formed per water molecule?

A

There are four: Two as a donor and two as an acceptor

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11
Q

What is the relative length for hydrogen bond vs covalent bonds?

A

Hydrogen bond interactions are over a greater length than covalent bonds

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12
Q

What must a hydrogen bond acceptor have?

A

A lone pair that must be in a hybridized orbital

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13
Q

Why does ice form a lattice?

A

Because of the regular orientation of hydrogen bonding

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14
Q

What are the hydrogen bonds like in water form?

A

Hydrogen bonds are constantly reforming and braking

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15
Q

How many hydrogen bonds per a water molecule are usually forming?

A

Usually 2-3 hydrogen bonds but can form up to four

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16
Q

What is energy like when releasing and forming hydrogen bonds?

A

There is an input of energy required to break hydrogen bonds and a release of energy when forming hydrogen bonds

17
Q

how many hydrogen bonds can a hydronium ion form?

A

Four: Three as a donor and one as an acceptor

18
Q

What are the two non-covalent biological interactions of importance?

A
  • Electrostatic forces

* Hydrophobic effects

19
Q

What are the three types of electrostatic forces?

A
  • Ionic interactions
  • Hydrogen bonds
  • Van der Waals
20
Q

What are the two types of Van Der Waals forces?

A
  • Dipole-Dipole interactions

* London dispersion forces

21
Q

What are Van der Waals interactions?

A

Interactions between permanent dipoles or induced dipoles

22
Q

What are Hydrophobic effects?

A

Interactions that favor bringing non polar groups together that have a preference for not interacting water

23
Q

What do Dipole Dipole interactions occur between?

A

Polar non-charged groups

24
Q

What do London dispersion forces occur between?

A

Nonpolar molecules that have an induced dipole