Lecture 19 Flashcards
How are selenoproteins made?
Selenium replaces the sulfur in amino acids
What are 2 examples of role selenium has with enzymes and proteins?
- Glutathione peroxidases
- prevents oxidative damage to phospholipids and cell damage
- antioxidant nutrient - Deiodinase for thyroid hormone (T4->T3)
How is NZ selenium intake for men and women?
For men intake is good, for women intake is slightly below the RDI
How would we know the soils are low in selenium?
It would be reflected in the selenium content of soil grown plants
Are fruit and vege good or poor sources of selenium?
Poor
What are examples of plants that accumulate selenium?
- Brazil nuts
- Nuts
- Mushrooms
- Garlic
How does the bioavailability of selenium in a Brazil nut compare to a Se supplement?
It is the same
What are rich sources of selenium?
Fish and organ meats
->muscle meats, dairy products
What % of selenium is absorbed?
80%, unregulated
What % of dietary selenium is excreted? How is it excreteed?
50-60% through the urine
What is Keshan’s disease and what is it a result of?
- Result of deficiency in Selenium
- Cardiomyopathy in children and pregnant women
Is Keshan’s disease seen in NZ? Why?
No, we have higher animal product intake in our diet
Describe the toxicity of Selenium
There is a narrow range between good - toxic amount
Toxicity is rare from the diet
What % of flouride is absorbed?
100%
What is the fluoridation recommendation for water?
0.7-1.0ppm
