Lecture 14 Antibiotic Resistant Microorganisms Flashcards
What are antibiotics
Compounds produced by microorganisms that kill or inhibit the growth of other microorganisms
70% of antibiotics are produced by
Streptomyces bacteria
Penicillin was first antibiotic and produced by
Penicillium notatum
How many known antibiotics
8000
Who discovered Penicillin
Alexander Fleming in 1928
Name the green mold that helped Alexander Fleming to discover Penicillin
Penicillium notatum
When did Fleming,Florey and Chain win Nobel prize
In 1945
Bactericidal
Kill microbes directly
Bacteriostatic
Prevent microbes from growing
Synergism occurs when
the effect of two drugs together is greater than the effect of either alone
Antagonism occurs when
the effect of two drugs together is less than the effect of either alone
Name an inhibitor of cell wall synthesis
Penicillin
Penicillin G requires what to be taken
An injection
Penicillin V required what to be taken
Can be taken orally
When did S. aureus became resistant to penicillin
In 1945 - two years after it was first widely used