Lecture 11 (Immune system) Flashcards

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1
Q

What does Susceptibility mean

A

Lack of resistance to a disease

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2
Q

What does Immunity mean

A

Ability to ward off a disease

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3
Q

What does Innate immunity mean

A

Defended against any pathogens

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4
Q

What does Adaptive Immunity mean

A

Immunity, resistant to a specific pathogen

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5
Q

What are Pathogens

A

agents that cause disease, infect a wide range of animals, including humans

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6
Q

When the immune system recognises foreign bodies what does it respond with

A

The production of immune cells and proteins

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7
Q

Do all animals have adaptive immunity or innate immunity

A

Innnate immunity

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8
Q

What is special about Vertebrates

A

They also have adaptive immunity

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9
Q

When is Innate Immunity presented

A

before any exposure to pathogens and is effective from the time of birth

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10
Q

What does Innate Immunity involve

A

nonspecific responses to pathogens

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11
Q

What does Innate Immunity consist of

A

•External barriers
•Internal cellular
•Chemical defenses

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12
Q

When does Adaptive immunity develop

A

after exposure to agents such as microbes, toxins, or other foreign substances

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13
Q

What does Adaptive immunity involve

A

A very specific response to pathogens

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14
Q

How does the Immune system recognise bacteria and fungi

A

Structures on their cell wall

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15
Q

Phagocytic cells recognize groups of pathogens by

A

TLRs, Toll-like receptors

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16
Q

Function of Eosinophils

A

Kill Parasites

17
Q

Name the different types of Phagocytic Cells

A

•Neutrophils
•Macrophages
•Dendritic cells

18
Q

Function of phagocytic Neutrophils

A

•Engulf and destroy pathogens

19
Q

Function of phagocytic Macrophages

A

Found throughout the body

20
Q

Function of phagocytic Dendritic cells

A

stimulate development of adaptive immunity

21
Q

What do Eosinophils discharge

A

Destructive enzymes

22
Q

adaptive response heavily relies on two types of lymphocytes, or white blood cells what are the two types called

A

•T cells
Mature in the Thymus above the heart

•B cells
Mature in the Bone marrow

23
Q

Antigens elicit a response from what two WBC

A

•B cell
•T cell

24
Q

The small accessible part of an antigen that binds to an antigen receptor is called an

A

Epitope

25
Q

Binding of a B cell antigen receptor to an antigen secretes a soluble form of a protein called

A

•An antibody or Immunoglobin

26
Q

Secreted antibodies are similar to B cell receptors but they lack what

A

Transmembrane regions that anchor receptors in the plasma membrane

27
Q

Function of Antibodies

A

They mark pathogens for destruction and/or phagocytosis - Opsonisation

28
Q

In Neutralization what do antibodies bind to

A

Viral surface proteins preventing infection of a host cell

29
Q

B cells can express five different forms (or classes) of immunoglobulin (Ig) with similar antigen-binding specificity what are these called

A

-IgD: Membrane bound
-IgM: First soluble class produced
-IgG: Second soluble class; most abundant
-IgA and IgE: Remaining soluble classes

30
Q

What are Vacinnes

A

Harmless derivatives of pathogenic microbes that stimulate the immune system to mount defenses against the harmful pathogen