Lawsonia and Moraxella Flashcards

1
Q

General characteristics of Lawsonia intraceullularis

A

slender, curved gram neg rod
obligate intracellular pathogen

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2
Q

What does Lawsonia intraceullularis cause?

A

acute hemorrhagic syndrome
subclinical conditions releated to poor production
proliferative enteropathy

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3
Q

What are the disease forms of Lawsonia intraceullularis in pigs?

A

acute: porcine hemorrhagic enteropathy
chronic: porcine intestinal adenomatosis

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4
Q

Clinical signs of Lawsonia intraceullularis

A

mostly subclinical
mild diarrhea
reduced weight gain

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5
Q

Diagnosis of porcine intestinal adenomatosis

A

bacteria detection in feces
histochemical and immunohistochemical detection
detection of IFN-y
detection of IgG

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6
Q

What disease does Lawsonia intraceullularis cause in horses?

A

equine proliferative enteritis - common in weanlings 4-7 months old

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7
Q

Clinical signs of equine proliferative enteropathy

A

diarrhea, depression, fever, reduced appetite, weight loss, swelling of abdomen and lower limbs, poor hair coat, intermittent colic

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8
Q

Diagnosis of Lawsonia intracellularis

A

histopathology, PCR, tissue culute, chick embryos

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9
Q

Treatment of Lawsonia intraceullularis

A

tetracyclines
erthromycine + rifampin
tylosin in feed prophylactically

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10
Q

Is there a vaccine available for Lawsonia intraceullularis?

A

yes - live avirulent oral vaccine
reduces severity of disease

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11
Q

What disease is caused by Moraxella bovis?

A

infectious bovine keratoconjunctivitis - pink eye

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12
Q

General characteristics of Moraxella

A

gram neg coccobacilli in pairs
aerobic
non motile

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13
Q

Does Moraxella require enriched media?

A

yes - containing blood or serum

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14
Q

Virulence of Moraxella

A

fimbriae

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15
Q

Pathogenesis of M. bovis

A

bacteria adhere to cornea
pitting
edema and lymphocytic infiltration
sloughing of tissue
ulcers
photophobia
discharge

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16
Q

Transmission of M. bovis

A

direct contact
aerosol
mechnical vectors
perpetuated with UV rays, tall grass
concurrent mycoplasama a/o viral infections

17
Q

Diagnosis of M. bovis

A

gram staining of lacrimal discharge
culture
PCR
fluorescine dye

18
Q

Treatment of M. bovis

A

susceptibility testing
long-acting oxytetracycline IM
oxytetracycline in feed
ceftiofur SC
florfenicol IM
topical gentamicin
subconjunctival penicillin antibiotics
eye patches

19
Q

Is there a vaccine for M. bovis?

A

yes - efficacy is not great