Chlamydia Flashcards

1
Q

General characteristics of chlamydia

A

obligate intracellular bacteria
gram neg- cocci or rod

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2
Q

Describe the elementary body form of chlamydia

A

metabolically inactive
infectious form

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3
Q

Describe the reticulate body form of chlamydia

A

metabolically active
reproductive form

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4
Q

Transmission of chlamydia

A

inhalation or interpersonal contact

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5
Q

Is chlamydia easily culturable?

A

no - can only be grown in yolk sacs or in cell culture
OBLIGATE INTRACEULLUAR PATHOGEN

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6
Q

Virulence factors of chlamydia

A

heamaglutinin
endotoxin
CMI causing tissue damage and inflammation

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7
Q

How do chlamydia cells enter the host?

A

enter as elementary bodies using receptor-mediated endocytosis

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8
Q

Where in the host cell does chlamydia reproduce?

A

host cell cytoplasm

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9
Q

Can chlamydia be shed in feces?

A

yes - for a long time

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10
Q

Laboratory diagnosis of chlamydia

A

wright-giema stain or modified ziehl-neelsen
PCR
IHC
ELISA
FA
culture

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11
Q

What are some concerns with serological tests for chlamydia?

A

concern with cross-reactivity of antibodies with other gram-neg bacteria

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12
Q

Treatment for chlamydia infections

A

quarantine
tetracyclines and fluorquinolones
concerns with bacterial clearance

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13
Q

Hosts of C. psittaci

A

birds
sheep
goat
pigs
cattle
humans
cats

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14
Q

What does C. psittaci cause in birds?

A

Psittacosis
parrot fever
AC
ornithosis
systemic illness

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15
Q

Symptoms of C. psittaci in birds

A

variable
lethargy
anorexia
ruffled feathers
death
ocular or nasal disacharge
diarrhea
green/yelllow urates
pericarditis, airsaculitis
hepatomegaly

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16
Q

What does C. abortus cause in cattle?

A

Sporatic bovine encephalomyelitis aka Buss disease

17
Q

Symptoms of Buss disease

A

encephalitis
fibrinous pleuritis
peritonitis
arthitis
pneumonia
conjunctivitis
abortion
infertility

18
Q

Which age of cattle are most at risk for SBE?

A

cattle 3 years or younger

19
Q

What conditions are caused by C. psittaci and C. abortus in sheep, goats, horses, cats and swine?

A

pneumonia
conjunctivitis
polyarthritis
abortion and infertility

20
Q

Is C. psittaci zoonotic?

A

yes - causes fatal pneumonia in humans

21
Q

What conditions are caused by C. pecorum in sheep and cattle?

A

sporatic encephalomyelitis
polyarthritis
diarrhea