Lab 2 Flashcards
def? the initial force of attraction that exists between a single Fab site on an antibody molecule and a single epitope site on the corresponding antigen
affinity
def? the overall strength of antigen-antibody binding and is the sum of the affinities of all the individual antibody-antigen combining sites
avidity
what is the 1st part in the process of aggulutination
sensitization
what is the second step in the process of agglutination
Lattice formation
order of highest avidity IgM, IgA, and IgG
IgM > IgA> IgG
what is avidity based on
size
what does IgG require to see a visible rxn
coomb’s regent
what is sensitivity.
the proportion of people who have a specific disease and have a positive test
what is the formula for sensitivity
true positives / true positives + false negatives)x100
what does sensitivity rule out
disease
formula for predictive measure for pos test
true positives/ true positives + false positives x100
true or false: urine can be disposed in a place without a biohazard symbol
t
when are serological test performed
when a pt does not have a lesion
what test is used to confirm nontreponemal test
serological test
what do treponemal serological test detect
Ab directed against T. palladium or against specific treponemal Ag
