CH.14 Flashcards

1
Q

how are immune complexes removed from the blood

A

phagocytosis, spleen

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2
Q

where do immune complexes accumulate if they are not removed

A

blood vessel walls and tissues where blood is filtered

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3
Q

what type of hypersensitivity rxn is removing immune complexes on filtering tissues

A

type III

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4
Q

what happens to the tissues once a type III rxn occurs

A

damages the tissue and causes inflammation

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5
Q

def? exaggerated immune response to a typically harmless ag

A

hypersensitivity

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6
Q

what type of hypersensitivity has immediate rxns

A

Type I, II, and III

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7
Q

what type of hypersensitivity has delayed rxn

A

type IV

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8
Q

what is the immune mediator for type I

A

IgE

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9
Q

type of hypersensitivity? Ag causes cross linking of IgE bound to mast cells which causes release of vasoactive mediators

A

Type I

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10
Q

what cause type I hypersensitivity rxn

A

allergies

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11
Q

what is the immune mediators for Type II hypersensitivity

A

IgG or IgM

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12
Q

type of hypersensitivity? Ab directed against cell surface ag mediates cell destruction (complement)

A

type II

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13
Q

what causes type II hypersensitivity rxns

A

blood transfusions

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14
Q

what is the immune mediator for type III rxn

A

immune complexes

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15
Q

type or hypersensitivity? Ag-ab complexes deposited in tissues induce complement and inflammation by infiltration of neutrophils

A

type III

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16
Q

what causes type III rxns

A

arthritis

17
Q

what is the immune mediator for type IV rxn

A

t cells

18
Q

type of hypersensitivity? sensitized T cells release cytokines that activate macrophages

A

Type IV

19
Q

what causes type IV rxns

A

dermatitis