L37,38 :pathogenic protazoans Flashcards

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1
Q

what is the active feeding stage of a protozoal parasite ?

A

trophozite

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2
Q

what is the inactive form of a protozoal parasite ?

A

oocyst/cyst

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3
Q

Entamoeba histolytica forms a cyst with how many nuclei ?

A

4

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4
Q

which non-pathogenic amoeba inhabits the oral cavity ?

A

entamoeba gingivalis

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5
Q

what are the presenting forms of entamoeba gingivalis ?

A

trophozite form only , no cyst

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6
Q

how is entamoeba gingivalis transmitted?

A

kissing or sharing eating utensils

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7
Q

entamoeba gingivalis is common in which group of people ?

A

people with poor oral hygiene and patients with periodontal disease . diseased periodontal tissue and associated actinomyces spp. provide a favorable environment for organism to develop

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8
Q

flagellated aerotolerant protazoan in oral cavity :

A

trichomonas tenax

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9
Q

presence of trichomonas tenax is considerably higher in __

A

patients with more dental calculus , coated tongue and poorly cleaned periodontal tissue

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10
Q

what is the obly state of trichomonas tenax?

A

flagellated vegitative state

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11
Q

intestinal protazoa ?

A

giardia lamblia

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12
Q

what disease does giardia lamblia cause?

A

giardiosis: watery foul smelling diarrhea + malabsorbtion syndrome : steotorrhea

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13
Q

smiling ghost appearance :

A

giardia lamblia

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14
Q

lab diagnosis of cryptosporidium hominis ?

A

acid fast staining ,

direct flurescent antibody enzyeme

immunoassy for antigen detection

PCR

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15
Q

Urogenital protozoans :

A

trichomonas vaginalis

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16
Q

diseases caused by trichomonas vaginalis and route of transmission ?

A

trichomoniosis
foul smelling greenish vaginal discharge in women , asymptomatic in men

route of transmission : sexual contact

17
Q

what organism causes toxiplasmosis ?

A

toxoplasma gondii

18
Q

which microorganism has members of the Felidae family as their definitive hosts ?

A

toxoplasma gondii (oocyst shed in cats feces )

19
Q

malaria causing plasmodium spp.:

A

P.falciparum (potentially deadly )
P.vivax
P.malariae
P.ovale

20
Q

which malaria causing plasmodium species is potentially deadly ?

A

P. falciparum

21
Q

asexual schizogony and sexual gametogony of plasmodium species occurs in :

A

humans

22
Q

sexual sporogony of plasmodium spp. occurs in :

A

mosquitos

23
Q

relapse of plasmodium infection occurs due to :

A

hypnozoites in liver

24
Q

what is the infective form of plasmodium spp.;

A

sporozoites

25
Q

how are plasmodium spp. transmitted?

A

female anopheles mosquitoes

26
Q

complications of infection by plasmodium falciparum :

A

more infected RBCs - occlusion of organ capillaries by RBC

massive hemorrhages and necrosis

cerebral malaria

hemoglobinuria : black water fever ( can lead to acute renal failure)

27
Q

gametocyte of plasmodium falciparum shape:

trophozite shape:

A

bean of banana shaped

kinda like a smiling cell , ironic

28
Q

which organism causes seeping sickness ?

A

west African sleeping sickness : tryponosoma bruci Ambiense
east african sleeping sickness :tryponosoma bruci rhodesiense

29
Q

how is Trypanosoma brucei transmitted ?

A

tsetse fly bite . it injects metacyclic trypomastigotes into skin tissue

30
Q

trypomastigots is seen where in early stages and where in late stages?

A

early: blood
late : CSF

31
Q

Vector of Trypanosoma cruzi ?

A

kissing bug / reduviid / Triatoma , deposits trypomastigotes in feces near bite wound (in blood)— amastigotes intracellularly

32
Q

what disease does leishmania cause?

A

kala-azan (visceral leishmaniasis )–>sleenomegaly , muscle wasting , and hyperpigmented skin

33
Q

vector of leishmania donovani:

reservoir for leishmania donovani :

A

sandfly

dogs , foxes and rodents

34
Q

life cycle of leishmania donovani :

A

sand fly : promastigotes –> fly bites human —> promastigotes enter blood macrophages , forming amostigotes (intracellular in humans)