L14 ( Lecture numbers are wrong btw ) : streptococci Flashcards

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1
Q

what classification of bacteria is streptococci and how are they arranged ?

A

gram positive bacteria in chains

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2
Q

how does streptoccoci react to :
coagulation test
catalase test

A

negative on both

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3
Q

in what aerobic conditions do streptococci grow?

A

they are facultative anaerobes meaning they grow both in the presense of oxygen and in its absence

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4
Q

bacteria are subdivided based on ___

A

C-carbohydrate antigen on their cell wall (A-U)

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5
Q

which bacteria falls under group A Beta-hymolytic streptococci ?

A

S. pyogenes

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6
Q

which bacteria falls under group B Beta-hemolytic streptococci ?

A

S. Agalacitae

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7
Q

which streptococci species is responsible for 90% of pharyngitis cases?

A

S. pyogenes

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8
Q

what component of S.pyogenes is responsible for inhibition of opsonization and cell lysis ?

A

M-protein

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9
Q

which components of S. pyogenes are responsible for adhesion ?

A

lipoteichoic acid
factor F ( fibronectin binding proteins )

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10
Q

which components of S.pyogenes are responsible for spread of organism through tissue ?

A

streptokinase
hyloronidase

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11
Q

SPE-A + SPE-C Result in___

A

fever , and red rassh seen in scarlet fever

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12
Q

SPE-A causes ____

A

toxic shock syndrome

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13
Q

SPE-B is present in -

A

“flesh eating “ necrotizing fascites

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14
Q

what cytolytic toxin of streptococci induces formation of anti-bodies?

A

Streptolysin O

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15
Q

what cytolytic toxin of streptococci is responsible for hemolysis ?

A

Streptolysin S

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16
Q

pathogenicity of S.pyogenes ::

A

pharyngitis
tonsillitis
sinusitis
otis media

cellulitis
necrosing fascitis
polydermal impetigo and eryspl—

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17
Q

what is the most common strep disease?

A

strep/sore throat

18
Q

describe impetigo

A

honey colored crusts

19
Q

how is strep throat spread?

A

saliva / nasal secretions

20
Q

what is the incubation period of strep throat ?

A

2-4 days

21
Q

S. pyogenes also causes:
-endocardidits (puerperal fever )
-myositis
-acute rheumatic fever ( 2 weeks after infection )
-glomerulonephritis (2-3 weeks after infection )

A
22
Q

glomerulonephritis developed 2-3 weeks after s.pyogenes infection is an example of which type of hypersensitivity ?

A

type III hypersensitivity ( antibodies against streptolysin O )

23
Q

what lab test can differentiate S.pyogenes from S.agalactiae?

A

sensitivity test against bacitracin :

S.pyogenes is sensitive while S. agalactiae is resistant

24
Q

which streptococcal bacteria is part of normal flora of vagina and lower GIT ?

A

S. agalactiae (5-30% of women )

25
Q

what component protects S.agalactiae bacteria from phagocytosis ?

A

polysaccharide capsule

26
Q

pathogenicity of S. agalactiae ::

A

neonatal meningitis
purperal sepsis
pneumonia

27
Q

S. agalactiae is CAMP test ____

A

positive

28
Q

Group D streptococcal bacteria can be categorized into 2 groups , which are ?

A

enterococcus

non-enterococcal

29
Q

examples of enterococcal bacteria :

A

S. fecalis
S. faecium

(UTI , intra-abdominal infections , pelvic infections )

they are normal flora in the GIT lower tract

(opportunistic/ nosocomial infections )

30
Q

example of non enterococcal bacteria :

A

S. Bovis (S. gallocyticus)—causes endocarditis especially in patients with colon carcenoma

31
Q

Give examples if alpha hemolytic streptococcal bacteria .

A

S. pneumoniae
S. viridans

32
Q

what’s the shape /arrangement of S.pnumoniae ?

A

Lanceloale capsulated bicocci

normal inhabitants of 5-40% of peoples upper resparatory tract

33
Q

give an example of a virulence factor of S. Pnumoniae .

A

IgA protease ( to protect itself since in enters through respiratory tract which contains a lot of secretions and therefore , IgA)

34
Q

Which streptococci could be non-hemolytic as well as alpha hemolytic ?

A

S. viridans

35
Q

where are S. VIRIDANS USUALLY FOUND IN NORMAL FLORA?

A

oral cavity and nasopharengeal flora

36
Q

what is the most common cause of sub-acute bacterial endocarditis >?

A

S. viridans

37
Q

which streptococci involves brain absesses ?

A

S. viridans and peptostreptococci

38
Q

which streptoccoci are involved in dental caries ?

A

S. viridans

39
Q

what lab test can differentiate between S. viridans and S. pnumoniae ?

A

sentitivity to optochin :

S.. viridans are resistant while S.pnumoniae is sensitive

40
Q

give an example of an anaerobic streptoccoi ?

A

peptostreptococci ( grows in microarophillic conditions as well

41
Q

where are peptostreptococci normally present ?

A

normal flora of mouth , gut , and female genital tract