L28:Hepatitis viruses Flashcards
what is the only DNA hepatitis virus ?
HBV
Which antigen is an important indicator of transmissibility when it comes to HBV infection?
E antigen (HBeAg)
what is the infectious form of HBV>?
Dane particle
HBV infection results in hepatocellular injury due to :
immune attack of CD8 T cells
life-long immunity against HBV (after infection) is mediated by ?
HBsAg antibodies
high rate of hepatocellular carcinoma occurs in :
chronic carriers
what’s the criteria for labelling a patient as a carrier for HBV?
presence of HBsAg in blood for more than 6 months
which group of HBV patients have high E antigen concentration and there for have a high probability of transmitting the disease?
chronic carriers
which hepatitis infection is dependent on hepatitis B being already present in the body ?
Hepatitis D , it cannot replicate on its own
describe the 2 types of hepatitis D infections that can occur .
coinfection with HBV :severe acute disease with low risk of chronic infection
superinfection on top of chronic HBV : Severe chronic liver disease (life threatening )
immunoglobulin for HBV infection ?
hyperimmune hepatitis B immune globulin (one dose)
post exposure prophylaxis for HBV :
hyperimmune hepatitis B immune globulin + vaccine
hepatitis C is from which family of viruses :
flavivridae
which hepatitis virus is a major cause of post transfusion hepatitis ?
HCV
which hepatitis virus is a typical enterovirus ?
HAV
What is the only hepatitis virus that can be cultivated in vitro?
HAV
which hepatitis infection causes infectious hepatitis ?
HAV
Groups at increased risk of infection by HAV :
travelers to developing countries
drug users
chronic liver disease patients
which hepatitis viruses have only one serotype ?
HAV , HEV
HEV is also called :
Enterically transmitted NANB or epidemic NANB hepatis
NANB bas
HEV is particularly severe in :
third trimester of pregnancy
which hepatitis viruses are enveloped ?
HBV HCV HDV
AND RESPONSIBLE FOR CHRONIC LIVER DISEASE
Which hepatitis virus has a helical structure ?
HDV
Which hepatitis viruses are transmitted through feco-oral route ?
HAV HEV
