L28:Hepatitis viruses Flashcards

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1
Q

what is the only DNA hepatitis virus ?

A

HBV

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2
Q

Which antigen is an important indicator of transmissibility when it comes to HBV infection?

A

E antigen (HBeAg)

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3
Q

what is the infectious form of HBV>?

A

Dane particle

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4
Q

HBV infection results in hepatocellular injury due to :

A

immune attack of CD8 T cells

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5
Q

life-long immunity against HBV (after infection) is mediated by ?

A

HBsAg antibodies

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6
Q

high rate of hepatocellular carcinoma occurs in :

A

chronic carriers

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7
Q

what’s the criteria for labelling a patient as a carrier for HBV?

A

presence of HBsAg in blood for more than 6 months

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8
Q

which group of HBV patients have high E antigen concentration and there for have a high probability of transmitting the disease?

A

chronic carriers

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9
Q

which hepatitis infection is dependent on hepatitis B being already present in the body ?

A

Hepatitis D , it cannot replicate on its own

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10
Q

describe the 2 types of hepatitis D infections that can occur .

A

coinfection with HBV :severe acute disease with low risk of chronic infection

superinfection on top of chronic HBV : Severe chronic liver disease (life threatening )

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11
Q

immunoglobulin for HBV infection ?

A

hyperimmune hepatitis B immune globulin (one dose)

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12
Q

post exposure prophylaxis for HBV :

A

hyperimmune hepatitis B immune globulin + vaccine

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13
Q

hepatitis C is from which family of viruses :

A

flavivridae

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14
Q

which hepatitis virus is a major cause of post transfusion hepatitis ?

A

HCV

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15
Q

which hepatitis virus is a typical enterovirus ?

A

HAV

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16
Q

What is the only hepatitis virus that can be cultivated in vitro?

A

HAV

17
Q

which hepatitis infection causes infectious hepatitis ?

A

HAV

18
Q

Groups at increased risk of infection by HAV :

A

travelers to developing countries

drug users

chronic liver disease patients

19
Q

which hepatitis viruses have only one serotype ?

A

HAV , HEV

20
Q

HEV is also called :

A

Enterically transmitted NANB or epidemic NANB hepatis

NANB bas

21
Q

HEV is particularly severe in :

A

third trimester of pregnancy

22
Q

which hepatitis viruses are enveloped ?

A

HBV HCV HDV

AND RESPONSIBLE FOR CHRONIC LIVER DISEASE

23
Q

Which hepatitis virus has a helical structure ?

A

HDV

24
Q

Which hepatitis viruses are transmitted through feco-oral route ?

A

HAV HEV