L16 & 17 : corynrbacterium and actinomyetes Flashcards

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1
Q

spore forming aerobic gram positive bacteria :

spore forming anaerobic gram positive bacteria :

non spore forming non-filimentous gram positive bacteria :

non-spore forming filimentous aerobic gram positive bacteria :

non spore forming filimentous anaerobic bacteria:

A

bacillus

clostredium

corynebacterium . listria

nocardia

actinomyces

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2
Q

whats inside the swollen end of C. diphtherea ?

A

phosphate polymers : volutin , ernst babe granules , metachromatic granules

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3
Q

who are the hosts of C. diphtherea ?

A

humans

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4
Q

where does C.diphtherea infection often stem from ?

A

carries

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5
Q

how is C. diphtheria transmitted?

A

inhilation or contact

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6
Q

what does C.diphtherieas exotoxin do to cells ?

A

prevent protein synthesis (coded by bacteriophage , beta phage toxin synthesized during lysogenic phase )

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7
Q

which bacteria produces a pseudo membrane in local inflammation on the mucosal surface of the throat ?

A

C. diphtherea , membrane can cause airway obstruction if it reaches the larynx

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8
Q

Diffusion of C.diphtherea exotoxin into blood can result in :”

A

myocarditis
peripheral neuritis
paralysis of arms and legs
visual disturbances

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9
Q

how is active immunity prophylaxis against C. diphtherea achieved ?

A

formol toxoid + pertissis vaccine + tetanus toxoid ( DTaP)

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10
Q

how is passive immunity against C. diphtherea achieved ?

A

by giving anti-toxin serum

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11
Q

which bacteria is described as the transitional form between bacteria and fungi ?

A

Actinomycetes

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12
Q

under what aerobic conditions does actinomycetes grow?

A

anerobic / microaerophillic

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13
Q

actinomycetes are non acid fast

A

fr

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14
Q

where is actinomycetes normally present ?

A

oral cavity ( A. israelli)
vagina
intestinal mucosa

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15
Q

which organism has a sunshine ray like apperance under microscope?

A

Actinomycetes

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16
Q

chronic granulomatous infection ;

A

actinomycosis

17
Q

what can cause an actinomycetes infection?

A

trauma , foreign bodies , or poor oral hygiene

18
Q

dental disease/ surgery or chronic mastoiditis can cause which type of actinomycosis ?>

A

cervicofacial actinomycosis

19
Q

how does farmers lung happen
?

A

hypersensitivity pneumonitis : imhilation of mouldy hay (actinomyces)

20
Q

whats the most common source of systemic and CNS nocardia infection?

A

nocardia asteroids (80% non cutaneous )

21
Q

whats the most virulent and most resistant form of nocardia ?

A

nocardia farcinica

22
Q

which type of nocardia affects the skin , and cutaneous lymphocutaneous tissue ?

A
23
Q

which type of nocardia affects the skin , and cutaneous lymphocutaneous tissue ?

A

nocardia brasiliensis

24
Q

which bacteria is partially acid fast ?

A

nocardia

25
Q

what are some factors that may predispose a patient to nocardia infection?

A

pre-existing lung disease (COPD)
chronic steroid use
transplant recipient
HIV / AIDS

26
Q

What illnesses can be caused by nocardia ?

A

lungs : pneumonia
skin : ulcer , nodules
cns : brain abscess
eyes : keroitis

27
Q

how does disseminated nocardia spread?

A

from lung to other organs through blood stream

28
Q

what is the source of nocardia ?

A

mud , compost , and rotting vegetables

29
Q

how is nocardia spread?

A

inhalation
innoculation into wound ( madura foot - actinomycotic mycetoma )

brain abscess

kidney infections