L13:Immunodeficiency diseases

Question 1

T cell deficiency will make the patient more susceptible to :?

Answer 1

intracellular pathogen infection

Question 2

what does thymic aplasia (di georges syndrome) result in ?

Answer 2

severe combined immunodeficiency

immunodeficiency with hypoparathyroidism

Question 3

chronic mucotaneous candidasis affects___

Answer 3

skin , nails , mucosa

Question 4

chronic mucotaneous candidasis results in deficit in ___

Answer 4

IL-17

Question 5

Brutons disease is an example of ____

Answer 5

x-linked agammaglobuinemia

Question 6

defect in B cells is inherited as ____

Answer 6

X-linked recesive genetic trait

Question 7

who is more at risk of inheriting an X-linked disease ?

Answer 7

Males

Question 8

what is the most common presenting infection of combined immunodeficiency ??

Answer 8

pneumonia

Question 9

how is severe combined immunodeficiency inherited?

Answer 9

As X-linked recessive pattern

Question 10

severe malnutrition can decrease synthesis of____

Answer 10

IgG

Question 11

How does aslpeenia affect immunity ?

Answer 11

antibody response to new antigens is generally suppressed but antibody response to previously encountered antigens is still intact

Question 12

malnutrition and liver failure decrease____ increasing susceptibility to____

Answer 12

decreases compliment serum proteins , increasing susceptibility to infection by pyogenic bacteria