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Microbiology > L26-27 DNA and RNA viruses > Flashcards

L26-27 DNA and RNA viruses Flashcards

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Biology 101 flashcards
1
Q

which viral infection causes oral sqamous papilloma / squamous cell carcinoma (verrucous carcinoma ?

A

papovaviruses

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2
Q

what is the shape of papovaviruses ?

A

icosahedral

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3
Q

how are papovaviruses transmitted ?

A

through direct contact or autoinoculation

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4
Q

how are adenoviruses spread?

A

respiratory and ocular secretions

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5
Q

what does an adenovirus infection cause ?

A

acute respiratory disease , pharyngitis , and conjunctivitis

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6
Q

herpes family of viruses include :

A

herpes simplex 1 and 2
varicella zoster virus
epstein barr virus
cytomegalo virus
human herpes virus 6,7,8

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7
Q

what does a herpes simplex 1 viral infection cause ?

A

acute gingivastomatitis : painful vascular lesions on gums , lips , and oral mucosa

herpatic kertoconjuctivitis

encephalitis

herpatic witlow

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8
Q

herpes simplex 2 infection causes:

A

genital herpes

aseptic meningitis

neonatal herpes

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9
Q

what does varicella-zoster infection result in ?

A

varicella (chickenpox) : primary infection usually in childhood)
zoster ( shingles) : reactivation of earlier varicella

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10
Q

how is a zoster infection different from varicella ?

A

shingles rash is similar to varicella but it is limited to skin innervated by a dorsal root ganglia (usually trigeminal)

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11
Q

what smear is used in order to see multinucleated giant cells in varicella-zoster infection?

A

tzank smear

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12
Q

PCR in screening for varicella-zoster virus looks for viral DNA in the ____

A

CSF

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13
Q

Which viral infection is characterized by lymphocytosis ?

A

Epstein barr virus

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14
Q

which viral infection is associated with human malignancies such as Burkits lymphoma , nasopharengeal carcinoma and oral hairy leukoplakia ?

A

Epstein barr virus

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15
Q

the latent form of epstein barr virus is present within ____

A

lymphocytes , B cells

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16
Q

high risk groups for symptomatic cytomegalovirus infection:

A

HIV / AIDS patients

organ transplant recipients

fatal to newborns if acquired congenitally

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17
Q

which viral infection has an owl eye apperance under the microscope?

A

cytomegalovirus

18
Q

which lymphocytes does human herpes virus 6 have affinity to?

A

both B and T cells

19
Q

which viral presence is usually asymptomatic in healthy adults ?

A

cytomegalovirus

20
Q

what diseases can be cause by human herpes virus 6?

A

mononucleosis with cervical lymphadenopathy

exanthem subitum (roseola infantum )

21
Q

human herpes virus 6 is present in :

A

saliva of most healthy adults

22
Q

what is HHV-7 associated with ?

A

rashes

23
Q

which lymphocytes are affected by HHV-7 ?

A

T cells

24
Q

which virus is associated with kaposis sarcoma ?

A

HHV-8
Also associated with vascular endothelial tumor which is common in HIV patients

25
Q

which group of viruses is responsible for influenza infection ?

A

orthomyxovirus

26
Q

orthomyxoviruses are subdivided into types A, B , and C based on :

A

nucleocapsid protein NP and

viral envelope matrix protein :protein M

27
Q

nomenclature of influenza viruses is based on :

A

hemogglutanin (H) and neuriminidase (N)

28
Q

which viruses have a spherical structure and segmented , 8 piece ssRNA (capable of genetic re-assortment ?

A

orthomyxoviruses

29
Q

which group of viruses includes mumps , measles and parainfulenza , RESPARITORY syncytial virus ?

A

paramyxoviruses

30
Q

describe the structure of paramyxoviruses :

A

pleomorphic
Single linear ssRNA

31
Q

influenza virus
possesses:
nucleocaspid shape:
transmission :

A

RNA polymerase

helical

respairatory aerosols

32
Q

what is the difference between antigen shift and antigen drift?

A

antigen shift is a major re-assortment of RNA segments while Antigen drift is a minor change or mutation in the RNA

33
Q

what diseases are caused by resparatory syncytial virus ?

A

pneumonia and bronchitis in infants

otitis media in children

33
Q

what diseases are caused by resparatory syncytial virus ?

A

pneumonia and bronchitis in infants

otitis media in children

34
Q

what are the complications of mumps viral infection ?

A

paratitis in one of or both parotid glands

35
Q

attenuated form of which virus is used in the measles mumps rubella vaccine ?

A

mumps virus

36
Q

what are the complications of measles ?

A

respiratory issues

neurological issues

gangrenous stomatitis and noma –> can lead to destruction of orofacial tissue and consequent disfigurement when paired with necrotizing ulcerative gingivitis , malnutrition and oral ulcers

rash

37
Q

rna virus = helical
dna virus = sphere

papillovirus : unenveloped

herpes: enveloped

orthomyxovirus : sphere

corona virus : enveloped

A

.

38
Q

group A coxsackie viruses cause:

A

herpangia : herpes like oropharengitis

hand food , and mouth disease

39
Q

what is the receptor for SARS coronavirus on the surface of cells ?

A

angiotensin converting enzyme 2

40
Q

pneumonia caused by SARS is charecterized by

A

diffuse edema resulting in hypoxia

41
Q

MERS is caused by MERS-CoV : BINDS TO cd26

A

Microbiology (30 decks)

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