Kirks Flashcards

1
Q

Oropharyngeal swallowing involve which muscles ?

A

Constriction of pharyngeal muscle and relaxation of cricopharyngeal muscle

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2
Q

Breeds at risk of dysphasia?

A

Golden (pharyngeal), cocker (cricopharyngeal), bouvier des Flandres (muscular dystrophy), boxer (inflammatory myopathy)

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3
Q

Which muscle is involve in achalasia ?

A

Inhability of cricopharyngeal muscle to open

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4
Q

Which enzyme contains helicobacter ?

A

Urease

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5
Q

Cobalamin pathway in cats

A

1) cobalamin release from food in the stomach
2) cobalamin binds to haptocorrin in the stomach
3) binds to intrinsic factor produce by the pancreas
4) travels to ileum

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6
Q

Treatment of tritrichomonas?

A

Ronidazole

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7
Q

Which breed is predisposed to immunoproliferative enteropathy?

A

Basenji

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8
Q

Which breed is predisposed to PLN/PLE complex ?

A

Soft wheaten terrier

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9
Q

Which breed are predisposed to hepatic amyloidosis?

A

Shar pei, abyssins and Siamese

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10
Q

What is the half life of ALT?

  • cats
  • dogs
A

6 hours

2,5 days

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11
Q

Which medication can result in a dose dépendant hepatitis?

A
Phenobarbital 
Azathioprine 
Azole fungal 
Acetaminophen 
Amiodarone
Lomustine
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12
Q

Which medication can result in idiosyncratic hepatitis?

A
Sulfa 
Carprofen 
Diazepam 
Zonisamide 
Methimazole
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13
Q

Which receptor is involve in hepatic uptake of copper ?

A

CTR1

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14
Q

Which location is associated with secondary copper accumulation?

Periportal or centrolubulair?

A

Periportal

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15
Q

Which molecule stores copper in liver and is induce by administration of zinc ?

A

Metallothioneins

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16
Q

Which 2 breeds are predisposed to intrahepatic shunts?

A

Irish wolfhounds

Australian Shepherd

17
Q

What mutation can predispose Shetland to mucocele?

A

ABCB4

18
Q

What coagulation test increases with hepatic lipidosis ?

A

PT

19
Q

Inherited mega esophagus is seen in which breeds ?

A

Wirehaired fox terriers and miniature schnauzer

20
Q

Where can ALP come from?

A

Kidney, liver, bone, placenta, steroids, intestinal

21
Q

Half life of ALP?

A

2.5 days

22
Q

What 2 system results in acid secretion?

A
  • H-K ATPase enzymes in parietal of oxyntic glands

- pepsinogen from the chief cells in the gastric mucosa

23
Q

What causes the release of the parietal cells?

A

Stimulation via acetylcholine (M3), gastrin (CCK) and histamine (H2) receptors in enterochromaffin like cell within lamina propria

24
Q

Which nerves are involve in swallowing ?

A

V VII IX X XII