Kirks Flashcards
Oropharyngeal swallowing involve which muscles ?
Constriction of pharyngeal muscle and relaxation of cricopharyngeal muscle
Breeds at risk of dysphasia?
Golden (pharyngeal), cocker (cricopharyngeal), bouvier des Flandres (muscular dystrophy), boxer (inflammatory myopathy)
Which muscle is involve in achalasia ?
Inhability of cricopharyngeal muscle to open
Which enzyme contains helicobacter ?
Urease
Cobalamin pathway in cats
1) cobalamin release from food in the stomach
2) cobalamin binds to haptocorrin in the stomach
3) binds to intrinsic factor produce by the pancreas
4) travels to ileum
Treatment of tritrichomonas?
Ronidazole
Which breed is predisposed to immunoproliferative enteropathy?
Basenji
Which breed is predisposed to PLN/PLE complex ?
Soft wheaten terrier
Which breed are predisposed to hepatic amyloidosis?
Shar pei, abyssins and Siamese
What is the half life of ALT?
- cats
- dogs
6 hours
2,5 days
Which medication can result in a dose dépendant hepatitis?
Phenobarbital Azathioprine Azole fungal Acetaminophen Amiodarone Lomustine
Which medication can result in idiosyncratic hepatitis?
Sulfa Carprofen Diazepam Zonisamide Methimazole
Which receptor is involve in hepatic uptake of copper ?
CTR1
Which location is associated with secondary copper accumulation?
Periportal or centrolubulair?
Periportal
Which molecule stores copper in liver and is induce by administration of zinc ?
Metallothioneins
Which 2 breeds are predisposed to intrahepatic shunts?
Irish wolfhounds
Australian Shepherd
What mutation can predispose Shetland to mucocele?
ABCB4
What coagulation test increases with hepatic lipidosis ?
PT
Inherited mega esophagus is seen in which breeds ?
Wirehaired fox terriers and miniature schnauzer
Where can ALP come from?
Kidney, liver, bone, placenta, steroids, intestinal
Half life of ALP?
2.5 days
What 2 system results in acid secretion?
- H-K ATPase enzymes in parietal of oxyntic glands
- pepsinogen from the chief cells in the gastric mucosa
What causes the release of the parietal cells?
Stimulation via acetylcholine (M3), gastrin (CCK) and histamine (H2) receptors in enterochromaffin like cell within lamina propria
Which nerves are involve in swallowing ?
V VII IX X XII
