Integumentary System Flashcards
The skin accounts for ____% of body weight
7%
What are the 3 layers of the skin from superficial to deep? What type of tissue are they?
epidermis: keratinized stratified squamous epithelium
dermis: connective tissue
hypodermis: areolar and adipose connective tissue
Functions of the skin?
- protection: cushions organs and protects from chemicals, H2O loss, UV radiation, and bumps
- regulation of body temp.
- excretion: urea, salts, and H2O lost through sweat
- absorption: vitamins, lead, mercury, poison ivy/oak
- production of vitamin D
- sensory reception: keeps us aware of conditions at body’s surface
The epidermis is composed of_________ and _______
90% keratinocytes
10% melanocytes
Where are keratinocytes located? What are their functions?
- located at stratum spinosum and dead at skin surface
- produce keratin for protection
Where are melanocytes located? What are their functions?
- located at stratum basale
- manufacture and secrete melanin
What are the layers of the epidermis (top to bottom)?
- Stratum corneum (cornified layer)
- Stratum lucidum (clear layer)
- Stratum granulosum (granular layer)
- Stratum spinosum (spiny layer)
- Stratum basale (basal layer)
Stratum corneum
- 25-30 cell layer thick of dead keratinocytes (keratin)
- continuously shed/ dandruff
- protects skin from abrasions and penetration
Stratum lucidum
- occurs in thick skin on palms of hands and soles of feet
- composed of a few rows of flat, dead keratinocytes
Stratum granulosum
- 1-5 layers of flat dying keratinocytes
- contains granules that release waterproofing glycolipid
Stratum spinosum
- 8-10 cell layers thick
- some mitosis
- contains thick bundle of intermediate filaments
- contains star shaped Langerhans cells; macrophage
Stratum basale
-attached to underlying dermis
-cells actively divide; single row of youngest keratinocytes
-contains melanocytes
~secrete melanin
Callus vs. blister
- thickening of epidermis due to repeated friction
- separation of epidermis from dermis by fluid filled pocket
What is psoriasis?
- autoimmune skin disorder
- keratinocytes divide and move more quickly through epidermis
- cells pile up on surface and resemble flaky silvery scales
Process of epidermal growth
- stem cells divide and produce keratinocytes
- they are then pushed to the surface and fill with keratin
- 4 week process
- 30-40k shed/ minute
What is the purpose of the dermis? What are its layers?
- strong and flexible connective tissue that is richly supplied with nerves and blood vessels
- holds body together like a body stocking
-papillary and reticular layer