integument system Flashcards
what is the integument system consist of?
cutaneous membrane(skin) +accessory structures
what are the functions of the system?
protection (forms barrier, immune response, prevents water loss), thermoregulation, sensation, storage, vitamin D synthesis, excretion
what are the three layers of integument?
epidermis, dermis, hypodermis
what are the three main cell types?
keratinocytes, melanocytyes, dendrtic cells
what are keratinocytes?
produce keratin, 30-40 day turnover, superficial cells are dead
what are the melanocytes?
produce pigment melanin, protects against UV radiation, creates tan
what are dendritic cells?
immune function, macrophages patrol the skin, protect against pathogens/ cancer
4-5 layers of the epidermis?
stratum corneum, stratum lucidum, stratum granulosum, stratum spinosum, stratum basale
what is the corneum layer?
up to 30 layers of dead keratinocytes, cell filled with keratin, protective (cells continually shed), may contain carotene
what is the lucidum layer?
few layers of thin, flat, dead keratinocytes, found only in thick skin, plantar and palmer regions
what is the granulosum layer?
keritinization begins here, keratohyalin granules, glycolipid granules secrete into ECF and prevent water loss,
what is the spinosum layer?
8-10 layers of tightly joined living keratinocytes, desmosomes, dendritic cells here
what is the basale layer?
single layer of keritinocytes and melanocytes, access to underlying c.t and mitosis, cell growth/replacement produced here
characteristics of the dermis layer?
2nd layer of skin, blood vessels/nerves here, thick layer of c.t, cells=fibroblasts and immune cells, various sensory receptors
what two layer is the dermis consist of?
papillary and reticular layer