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Pulmonary Midterm > INSTIs > Flashcards

INSTIs Flashcards

1
Q

MOA of class

A

Inhibit strand transfer and prevent integration of reverse-transcribed HIV DNA into chromosomes of host cell.

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2
Q

All end in

A

Gravir

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3
Q

Dolutagravir

A

Treat naive pts when combo w/:

Tenofovir/emtricitabine
Abacavir/lamuvudine

14hr half life

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4
Q

Elvitagravir

A

Combo pill only

Requires boosting to work well- cobicistat (inhibit CYP3A4)

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5
Q

Raltegravir

A

Pregos**

Preferred treatment for naive pts beginning HAART

9 hr half life

Muscle aches

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Pulmonary Midterm (16 decks)

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