Corticosteroids C/A

Question 1

MOA

Answer 1

Inhibition of production of inflammatory cytokines —> decreases epsinophils, mast cells, and inflammation over all.

Question 2

Systemic- prednisone

Answer 2

Give in Asthma emergencies

Don’t give chronically

Can get oral candidiasis/muscle wasting/adrenal suppression/fat redistribution

Question 3

Beclomethasone, budesonide, ciclesonide, flunisolide, fluticasone, mometasone, triamcinolone

Answer 3

Topically active

Inhaled

Can get candidiasis (treat w/ azole)

Flu-nasal spray, for allergic rhinitis

Question 4

Ciclesonide

Answer 4

Improve all indices of asthma control

Give is if pt needs more than occasional albuterol (only works if compliant)

Question 5

Combos with long acting B Agonists

Answer 5

Flu + salm

Bud + form