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Pulmonary Midterm > Fungi-echinocandins > Flashcards

Fungi-echinocandins Flashcards

1
Q

MOA

A

Inhibit glucan synthase, (which inhibits fungal cell Wall synthesis) —> cell death

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2
Q

Spectrum

A

Candida

Aspergillus

NOT neoformans or mucor

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3
Q

How you GIVE

A

Only IV

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4
Q

Adverse effects

A

Well tolerated

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5
Q

Caspofungin

A

Invasive aspergillosis*****

Not primary treatment

9-11 hr half life

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6
Q

Micafungin

A

Mucocutaneous candidiasis

Candida

BM transplant pts

Half life 11-15 hrs

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7
Q

Anidulafungin

A

Esophageal candidiasis and invasive candidiasis

Half life 24-48 hrs

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Pulmonary Midterm (16 decks)

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