Inhalant Anesthetics Flashcards
Isoflurane MAC
Dog 1.3-1.6%
Horse 2.3%
Isoflurane Hepatic Metabolism
0.2%
Isoflurane Blood:Gas Solubility
1.4
Isoflurane Vapor Pressure
240
Isoflurane Therapeutic Use
most commonly used anesthetic agent
Isoflurane onset and offset of action
medium
Sevoflurane MAC
2.3-2.6%
Sevoflurane Hepatic Metabolism
3%
Sevoflurane Blood:Gas solubility
0.68
Sevoflurane Vapor Preessure
160
Adverse Effects of Sevoflurane
minimal adverse effects
Sevoflurane benefits
does not increase arrhythmogenicity
does not cause airway irritation
Halothane MAC
0.86%
Halothane Hepatic Methabolism
40%
Halothane Blood:Gas solubility
2.54
Halothane Vapor Pressure
243
Halothane Adverse Effects
CVS depression and arrhythmias
Halothane hepatitis - immune reaction to metabolites
Halothane considerations
preservative: thymol - accumulates in vaporizers
Desflurane MAC
dogs: 7.2%
horses: 8.1%
pigs: 10%
Desflurane Blood:Gas solubility
0.45
Desflurane therapeutic use
greater precision of anesthetic depth
Desflurane adverse effects
dose dependent respiratory depression
increased heart rate
vasodilation
Benefits of Desflurane
no arrhythmias
Considerations when using desflurane
high vapor pressure requires controlled pressurized vaporizer for delivery
MOA of all inhalant anesthetics
GABA-A agonists
Methoxyflurane Therapeutic Uses
analgesia at subanestheic doses
Methoxyflurane Blood:Gas solubility
very high = prolonged induction and recovery
